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| 2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE Basic information |
| Product Name: | 2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE | | Synonyms: | XYLOMETAZOLINE;2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE;AKOS BBS-00000259;XYLOMETAZOLINEANDITSHYDROCHLORIDE;Xylometazoline (base and/or unspecified salts);1h-imidazole,2-((4-(1,1-dimethylethyl)-2,6-dimethylphenyl)methyl)-4,5-dihydr;2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazolin;2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline | | CAS: | 526-36-3 | | MF: | C16H24N2 | | MW: | 244.38 | | EINECS: | 208-390-6 | | Product Categories: | | Mol File: | 526-36-3.mol |
| 2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE Chemical Properties |
| Melting point | 131-133° | | Boiling point | 394.2±21.0 °C(Predicted) | | density | 1.00±0.1 g/cm3(Predicted) | | pka | pKa 10.6±0.1(H2O
t = 22.0) (Uncertain) | | CAS DataBase Reference | 526-36-3 |
| Toxicity | LD50 oral in mouse: 215mg/kg |
| 2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE Usage And Synthesis |
| Uses | Adrenergic (vasoconstrictor). | | Uses | Xylometazoline is used for rhinitis, laryngitis, sinusitis, inflammation of antrum of
Highmore, and allergic illnesses of the nasal cavity and throat. | | Brand name | Neo-Synephrine II (Sterling Winthrop); Otrivin
Hydrochloride (Ciba-Geigy). | | Synthesis | Xylometazoline, 2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazoline
(11.1.40), is also synthesized in a single reaction by cyclocondensation of 4-tert-butyl-2,6-
dimethylbenzylcyanide with ethylendiamine [43,44]. |
| 2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE Preparation Products And Raw materials |
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