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| 4-CHLORO-1-NAPHTHOL Basic information |
| 4-CHLORO-1-NAPHTHOL Chemical Properties |
| Melting point | 118-121 °C(lit.) | | Boiling point | 254.41°C (rough estimate) | | density | 密度 | | refractive index | 1.4575 (estimate) | | Fp | 73 °C | | storage temp. | -20°C | | solubility | methanol: 50 mg/mL, clear, colorless to very faintly yellow | | form | tablets (~32 mg each) | | pka | 9.11±0.40(Predicted) | | color | Off-white to gray to light brown | | BRN | 509750 | | CAS DataBase Reference | 604-44-4(CAS DataBase Reference) | | EPA Substance Registry System | 1-Naphthalenol, 4-chloro- (604-44-4) |
| 4-CHLORO-1-NAPHTHOL Usage And Synthesis |
| Chemical Properties | Off white to tan crystals | | Uses | 4-Chloro-1-naphthol has been used to visualize protein bands in western blotting. It has also been used in staining polyvinylidene fluoride (PVDF) membrane by Nakane method. | | Uses | Suitable for visualizing protein-peroxidase conjugates in western blotting. | | Synthesis Reference(s) | Tetrahedron, 38, p. 2347, 1982 DOI: 10.1016/0040-4020(82)87012-9 | | General Description | 4-Chloro-1-naphthol is primarily used for the detection of proteins, it gives a characteristic purple precipitate and the reactions are easily controllable. It can be used as a substitute for benzidine compounds, which are considered to be carcinogenic. | | Biochem/physiol Actions | 4-Chloro-1-naphthol serves as a substrate for horseradish peroxidase. | | Purification Methods | Crystallise the naphthol from EtOH or CHCl3. [Beilstein 6 H 611, 6 II 582, 6 III 2933, 6 IV 4233.] |
| 4-CHLORO-1-NAPHTHOL Preparation Products And Raw materials |
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