DULCITOL

DULCITOL
  • CAS No.:6051-87-2
Other grades of this product :
DULCITOL Basic information
Product Name:DULCITOL
Synonyms:1H-Naphtho[2,1-b]pyran-1-one,3-phenyl-;3-Phenyl-1H-benzo[f]chromen-1-one;3-Phenyl-1H-naphtho(2,1-b)pyran-1-one;3-Phenyl-1H-naphtho[2,1-b]pyran-1-one;3-Phenyl-benzo[f]chromen-1-one;β-Naphthoflavon;5,6-BENZOFLAVONE;β-Naphthoflavone, 99+%
CAS:6051-87-2
MF:C19H12O2
MW:272.3
EINECS:227-958-4
Product Categories:Flavones;Phase I Enzyme Inducer;Phase I Enzyme Inducers;Benzopyrans;Bioactive Small Molecules;Building Blocks;Cancer Research;Cell Biology;Chemical Synthesis;Chemopreventive Agents;Heterocyclic Building Blocks;Multidrug Resistance;N
Mol File:6051-87-2.mol
DULCITOL Chemical Properties
Melting point 164-166 °C (lit.)
Boiling point 275-280 °C (1 mmHg)
density 1.1382 (rough estimate)
refractive index 1.5510 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly, Heated)
form Crystalline Powder
color yellow to tan
BRN 18991
CAS DataBase Reference6051-87-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi,C,F
Risk Statements 22-34-11
Safety Statements 24/25-45-36/37/39-26-16
WGK Germany 3
RTECS QL6200000
3-10
Hazard Note Irritant
HS Code 29329900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
DULCITOL Usage And Synthesis
Chemical PropertiesSLIGHTLY BEIGE CRYSTALLINE POWDER
Usesbeta-Naphthoflavone is a Cytochrome P450 enzyme system inducer. It can also be used in biological study of novel dual-color luciferase reporter assay for simultaneous detection of estrogen and aryl hydrocarbon receptor activation.
DefinitionChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
General Descriptionβ-Naphthoflavone is a polyaromatic hydrocarbon.
Biochem/physiol Actionsβ-Naphthoflavone (BNF) is an exogenous ligand for aryl hydrocarbon receptor (AhR) in humans. It is an inducer of phase I detoxification enzymes (CYPs) and phase II enzymes (UDP-GTs) and NAD(P)H-dependent quinone oxyreductase-1(NQO1). It also induces cytochrome P450 (Cyp1a). BNF represses the expression of Duchenne muscular dystrophy gene, dystrophin (Dp)71 by altering the binding of the transcription factors.
DULCITOL Preparation Products And Raw materials

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