5-Methyl-2'-deoxycytidine

5-Methyl-2'-deoxycytidine
  • CAS No.:838-07-3

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
5-Methyl-2'-deoxycytidine Basic information
Product Name:5-Methyl-2'-deoxycytidine
Synonyms:5-METHYL-DC;5-METHYL-2'-DEXOYCYTIDINE;5-METHYL-2'-DEOXYCYTIDINE;4-AMINO-1-[(2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-METHYL-PYRIMIDIN-2-ONE;2'-DEOXY-5-METHYLCYTIDINE;2’-deoxy-5-methyl-cytidin;5-Me-2'-deoxycytidine;2'-Deoxy-5-methylcytidine, ≥99%(HPLC)
CAS:838-07-3
MF:C10H15N3O4
MW:241.24
EINECS:212-655-1
Product Categories:Bases & Related Reagents;Heterocycles;Biochemistry;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents
Mol File:838-07-3.mol
5-Methyl-2'-deoxycytidine Chemical Properties
Melting point 217-219 °C(lit.)
Boiling point 492.8±55.0 °C(Predicted)
density 1?+-.0.1 g/cm3(Predicted)
refractive index 44 ° (C=1.4, H2O)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly)
form Powder
pkapK1:4.33 (25°C)
color White to Off-white
Water Solubility Soluble in water.
Stability:Hygroscopic
CAS DataBase Reference838-07-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
RTECS HA3860000
HS Code 29389090
MSDS Information
ProviderLanguage
SigmaAldrich English
5-Methyl-2'-deoxycytidine Usage And Synthesis
Description5-Methyl-2'-deoxycytidine is a nucleoside analogue that inhibits the synthesis of DNA. 5-Methyl-2'-deoxycytidine prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules.
Chemical PropertiesWhite Solid
Uses5-Methyl-2'-deoxycytidine is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo DNA methylation. It has been used in epigenetics research to investigate the dynamics of DNA methylation pattern in the control of gene expression.
Uses5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation.
UsesA Cytidine (C998300) analog and also an isostere of Thymidine (T412000).
5-Methyl-2'-deoxycytidine Preparation Products And Raw materials
Preparation Products5-METHYLCYTOSINE-->5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE

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