Other grades of this product :
| N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE Basic information |
| Product Name: | N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE | | Synonyms: | N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE;Biotin-PEG4-amine;(+)-BIOTIN-PEG3-AMINE;(+)-Biotin-PEG3-amine;(+)-Biotin-PEG3-CH2CH2NH2;(+)-Biotinyl 3,6,9-trioxaundecanediamine;Biotin-PEG3-NH2;N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide | | CAS: | 359860-27-8 | | MF: | C18H34N4O5S | | MW: | 418.55 | | EINECS: | | Product Categories: | peg;SiChem | | Mol File: | 359860-27-8.mol |
| N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE Chemical Properties |
| Melting point | 101-103°C | | Boiling point | 705.8±60.0 °C(Predicted) | | density | 1.166±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Methanol (Slightly) | | pka | 13.90±0.40(Predicted) | | form | Solid | | color | Pale Yellow to Pale Beige | | CAS DataBase Reference | 359860-27-8 |
| N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE Usage And Synthesis |
| Description | Biotin-PEG3-amine is reactive with NHS ester or carboxylic acid in the presence of EDC or HATU. PEG3 increases aqueous solubility of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. | | Uses | (+)-Biotinyl 3,6,9-Trioxaundecanediamine is a biotin derivative and is used as a reagent in the synthesis of a potent, covalent BTK inhibitor for B-cell lymphoma. |
| N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE Preparation Products And Raw materials |
| Raw materials | BIOTIN-NHS-->1,11-DIAZIDO-3,6,9-TRIOXAUNDECANE-->tert-Butyl (13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecyl)carbamate-->EZ-LINK (TM) PFP-BIOTIN, 50 MG-->Biotin-PEG4-N3-->11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE-->5,8,11-Trioxa-2-azatridecanoic,13-amino,1,1-dimethylethyl ester-->DIETHYLENE GLYCOL BIS(2-CHLOROETHYL) ETHER-->3,6,9-trioxaundecamethylenediamine-->Bis[2-(2-hydroxyethoxy)ethyl] ether-->D-Biotin |
|
日本语
한국어
Français
Deutsch
España
Türkiye