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| 2-amino-N-(2,2,2-trifluoroethyl)acetamide Basic information |
| 2-amino-N-(2,2,2-trifluoroethyl)acetamide Chemical Properties |
| Boiling point | 227.5±40.0 °C(Predicted) | | density | 1.294±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 12.87±0.46(Predicted) |
| 2-amino-N-(2,2,2-trifluoroethyl)acetamide Usage And Synthesis |
| Uses | 2-amino-N-(2,2,2-trifluoroethyl) acetamide, which is usually stable in the form of salt, is a key intermediate in the synthesis of fluralaner, a new broad-spectrum veterinary insecticide. | | Preparation | The method of preparing 2-amino-N-(2,2,2-trifluoroethyl) acetamide and its salt is to react the glycine protected by N-phthalyl group with trifluoroethylamine or its salt to form an amide, and remove the protective group under the action of hydrated fibril to obtain the crude product of 2- amino-N-(2,2,2-trifluoroethyl) acetamide.The crude product can be salted with acid to get a salt of 2-amino-N-(2,2, 2-trifluoroethyl) acetamide, and finally add a base to dissociate pure 2-amino-N-(2,2, 2-trifluoroethyl) ethylkuroamine.
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| 2-amino-N-(2,2,2-trifluoroethyl)acetamide Preparation Products And Raw materials |
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