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| DISUCCINIMIDYL SUBERATE Basic information |
| DISUCCINIMIDYL SUBERATE Chemical Properties |
| Melting point | 169-170°C | | Boiling point | 513.5±60.0 °C(Predicted) | | density | 1.295 g/cm3 | | storage temp. | 2-8°C | | solubility | chloroform: 50 mg/mL | | form | powder | | color | White to Almost white | | Water Solubility | Insoluble in water. Soluble in chloroform: 50 mg/mL. | | InChIKey | ZWIBGKZDAWNIFC-UHFFFAOYSA-N | | CAS DataBase Reference | 68528-80-3 |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29171900 |
| DISUCCINIMIDYL SUBERATE Usage And Synthesis |
| Description | DSS Crosslinker is a membrane permeable, noncleavable crosslinker. The NHS ester groups are reactive toward primary amines. | | Uses | Suberic acid bis(N-hydroxysuccinimide ester) has been:- supplemented in pierce lysis buffer used for immunoprecipitation
- used to conjugate the oligonucleotide standards to gelatin
- used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers
| | Uses | Disuccinimidyl suberate (DSS) is a bifunctional cross-linking reagent which contains two N-hydroxysuccinimide esters that are reactive toward primary amines. DSS is membrane-permeable and is commonly used to cross-link proteins in intact cells. | | Uses | Disuccinimidyl suberate is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm. | | General Description | Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker. |
| DISUCCINIMIDYL SUBERATE Preparation Products And Raw materials |
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