5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester

CAS No.：756526-02-0

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5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester Basic information

Product Name:	5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester
Synonyms:	5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester;5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(9H-fluoren-9-ylMethyl) ester;FMoc-NH-PEG8-CH2CH2COOH;Fmoc-N-amido-PEG8-acid;5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid;Fmoc-PEG8-CH2CH2COOH;Fmoc-PEG8-propionic acid;Fmoc-NH-(PEG)₈-CH₂CH₂COOH
CAS:	756526-02-0
MF:	C34H49NO12
MW:	663.75
EINECS:
Product Categories:	peg
Mol File:	756526-02-0.mol

5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester Chemical Properties

Boiling point	781.1±60.0 °C(Predicted)
density	1.190±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	Sealed in dry,Store in freezer, under -20°C
pka	4.28±0.10(Predicted)

Safety Information

HS Code

2924297099

MSDS Information

5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester Usage And Synthesis

Description

Fmoc-N-amido-PEG8-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Fmoc-NH-PEG8-CH2CH2COOH is used in synthesis of protein-antiviral compound conjugates.

5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester Preparation Products And Raw materials

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