6-Hydroxycoumarin

6-Hydroxycoumarin
  • CAS No.:6093-68-1
Other grades of this product :
6-Hydroxycoumarin Basic information
Product Name:6-Hydroxycoumarin
Synonyms:2H-1-Benzopyran-2-one, 6-hydroxy-;6-HYDROXY-2H-CHROMEN-2-ONE;6-HYDROXYCOUMARIN;6-Hydroxy-2H-chromen-2-one 97%;6-Hydroxy-2H-1-benzopyran-2-one;6-hydroxychromen-2-one;HYDROXYCOUMARIN, 6-(RG);6-Hydroxycoumarin 97%
CAS:6093-68-1
MF:C9H6O3
MW:162.14
EINECS:
Product Categories:Coumarins;Fused Ring Systems;Building Blocks;Heterocyclic Building Blocks
Mol File:6093-68-1.mol
6-Hydroxycoumarin Chemical Properties
Melting point 249-253 °C (lit.)
Boiling point 248.82°C (rough estimate)
density 1.2500
refractive index 1.5380 (estimate)
storage temp. Sealed in dry,Room Temperature
pka8.92±0.20(Predicted)
λmax349nm(EtOH)(lit.)
CAS DataBase Reference6093-68-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
Hazard Note Irritant
HS Code 29322010
MSDS Information
ProviderLanguage
SigmaAldrich English
6-Hydroxycoumarin Usage And Synthesis
Description6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity.
Occurrence6-Hydroxycoumarin is a natural product found in Grevillea robusta and Amburana cearensis with data available.
Uses6-Hydroxycoumarin (cas# 6093-68-1) is a compound useful in organic synthesis.
Preparation(1) synthesis of 6-aminocoumarins:In polar solvent, using 6- nitroscumarin as raw material, using hydrazine hydrate as hydrogen Source, is reducing catalyst using ferric chloride (FeCl36H2O), at ambient pressure reduces 6-nitroscumarin, prepare 6- aminocoumarins;(2) synthesis of 6-Hydroxycoumarins:In sulfuric acid solution, one-step method is by 6-aminocoumarins after diazo-reaction Direct hydrolysis, prepares 6-Hydroxycoumarins in high yield.The preparation method of 6 Hydroxycoumarins
6-Hydroxycoumarin Preparation Products And Raw materials
Raw materialsHydrazine hydrate-->Ferric chloride-->6-aminocoumarin

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