Bis(NHS)PEG5

Bis(NHS)PEG5
  • CAS No.:756526-03-1
Other grades of this product :
Bis(NHS)PEG5 Basic information
Product Name:Bis(NHS)PEG5
Synonyms:Bis(NHS)PEG5;Bis-PEG5-NHS ester;Bis-PEG6-NHS ester;Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16-pentaoxanonadecane-1,19-dioate;BIS-PEG5-NHS;NHS-PEG5-NHS;Bis-dPEG(R)5-NHS ester;PEG5 BIS-NHS ESTER
CAS:756526-03-1
MF:C22H32N2O13
MW:532.5
EINECS:
Product Categories:Homobifunctional PEG
Mol File:756526-03-1.mol
Bis(NHS)PEG5 Chemical Properties
storage temp. -20°C
solubility Soluble in DMSO, DCM, DMF
form solid or viscous liquid
color Colorless to Almost colorless
CAS DataBase Reference756526-03-1
Safety Information
MSDS Information
Bis(NHS)PEG5 Usage And Synthesis
DescriptionBis-PEG5-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
UsesBis(NHS)PEG5 is used in targeting M2-like tumor-associated macrophages by using melittin-based pro-apoptotic peptide conjugates with anti-cancer drugs,
General DescriptionBy contrast to typical PEG reagents that contain heterogeneous mixtures of different PEG chain lengths, this PEG reagent is a homogeneous compound of defined molecular weight and spacer arm length, providing greater precision in optimization and characterization of crosslinking applications. Homobifunctional crosslinkers containing N-hydroxysuccinimide (NHS) esters are often used for low-resolution 3-D studies of protein structure and protein interaction analysis.
Bis(NHS)PEG5 Preparation Products And Raw materials

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