| TCO-carbonate Basic information |
| Product Name: | TCO-carbonate |
| Synonyms: | (E)-4-Cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl ester carbonic acid;(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate;TCO-carbonate;TCO-NHS;TCO-N-hydroxysuccinimidyl carbonate;trans-4-Cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl carbonate;TCO-NHS ester;TCO4 - NHS carbonate / EQUATORIAL isomer |
| CAS: | 1191901-33-3 |
| MF: | C13H17NO5 |
| MW: | 267.28 |
| EINECS: | |
| Product Categories: | SiChem |
| Mol File: | 1191901-33-3.mol |
| TCO-carbonate Chemical Properties |
| Melting point | 90-105°C |
| Boiling point | 369.1±45.0 °C(Predicted) |
| density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| Safety Information |
| WGK Germany | 3 |
| MSDS Information |
| TCO-carbonate Usage And Synthesis |
| Description | TCO-NHS Ester is an popular reagent to label amine-containing compound or biomolecule, TCOI enable fast click chemistry with tetrazine. |
| Uses | Succinimidyl carbonate/NHS functionalized cyclooctene derivative for incorporation of the cyclooctene moiety into amine containing compounds or biomolecules. Cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1,2,4,5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging. |
| TCO-carbonate Preparation Products And Raw materials |
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