TCO-carbonate

TCO-carbonate
  • CAS No.:1191901-33-3
Other grades of this product :

TCO-carbonate Basic information
Product Name:TCO-carbonate
Synonyms:(E)-4-Cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl ester carbonic acid;(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate;TCO-carbonate;TCO-NHS;TCO-N-hydroxysuccinimidyl carbonate;trans-4-Cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl carbonate;TCO-NHS ester;TCO4 - NHS carbonate / EQUATORIAL isomer
CAS:1191901-33-3
MF:C13H17NO5
MW:267.28
EINECS:
Product Categories:SiChem
Mol File:1191901-33-3.mol
TCO-carbonate Chemical Properties
Melting point 90-105°C
Boiling point 369.1±45.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
storage temp. -20°C
Safety Information
WGK Germany 3
MSDS Information
TCO-carbonate Usage And Synthesis
DescriptionTCO-NHS Ester is an popular reagent to label amine-containing compound or biomolecule, TCOI enable fast click chemistry with tetrazine.
UsesSuccinimidyl carbonate/NHS functionalized cyclooctene derivative for incorporation of the cyclooctene moiety into amine containing compounds or biomolecules. Cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1,2,4,5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.
TCO-carbonate Preparation Products And Raw materials

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