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| Hydroxy-PEG2-CH2CO2t-Bu Basic information |
| Product Name: | Hydroxy-PEG2-CH2CO2t-Bu | | Synonyms: | Hydroxy-PEG2-CH2COOtBu;HO-PEG2-CH2COOtBu;tert-butyl 2-(2-(2-hydroxyethoxy)ethoxy)acetate;OH-PEG2-CH2COOtBu;Hydroxy-PEG2-CH2CO2t-Bu;Hydroxy-PEG2-CH2-Boc;Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester;Acetic acid, [2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester | | CAS: | 149299-82-1 | | MF: | C10H20O5 | | MW: | 220.26 | | EINECS: | | Product Categories: | peg | | Mol File: | 149299-82-1.mol |
| Hydroxy-PEG2-CH2CO2t-Bu Chemical Properties |
| Boiling point | 306.1±22.0 °C(Predicted) | | density | 1.062±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | pka | 14.35±0.10(Predicted) |
| Hydroxy-PEG2-CH2CO2t-Bu Usage And Synthesis |
| Description | Hydroxy-PEG2-CH2CO2tBu is a PEG linker containing a hydroxyl group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions. | | Uses | Hydroxy-PEG2-CH2CO2tBu was a useful reagent in the study for potentiator-corrector agonist of cystic fibrosis mutant protein ΔF508-CFTR preparation. |
| Hydroxy-PEG2-CH2CO2t-Bu Preparation Products And Raw materials |
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