Thiol-PEG2-acid

CAS No.：1379649-73-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Thiol-PEG2-acid Basic information

Product Name:	Thiol-PEG2-acid
Synonyms:	Thiol-PEG2-acid;HS-PEG2-CH2CH2COOH;SH-PEG2-COOH;HS-PEG2-COOH;Propanoic acid, 3-[2-(2-mercaptoethoxy)ethoxy]-
CAS:	1379649-73-6
MF:	C7H14O4S
MW:	194.25
EINECS:
Product Categories:	peg
Mol File:	1379649-73-6.mol

Thiol-PEG2-acid Chemical Properties

Boiling point	329.0±32.0 °C(Predicted)
density	1.173±0.06 g/cm3(Predicted)
storage temp.	Refrigerator, under inert atmosphere
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Oil
pka	4.27±0.10(Predicted)
color	Colourless
Stability:	Air Sensitive

Safety Information

HS Code

2930909899

MSDS Information

Thiol-PEG2-acid Usage And Synthesis

Description

Thiol-PEG2-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Thiol-PEG2-acid Preparation Products And Raw materials

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