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| 1-Methylindole Basic information |
| 1-Methylindole Chemical Properties |
| Melting point | 61.2°C (estimate) | | Boiling point | 133 °C26 mm Hg(lit.) | | density | 1.051 g/mL at 20 °C(lit.) | | refractive index | n20/D 1.606(lit.) | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | Liquid, May Develop Some Turbidity or Precipitate | | color | Colorless to white | | Water Solubility | insoluble | | Sensitive | Light Sensitive | | BRN | 111026 | | Stability: | Light sensitive. Combustible. Incompatible with strong oxidizing agents. | | InChIKey | BLRHMMGNCXNXJL-UHFFFAOYSA-N | | CAS DataBase Reference | 603-76-9(CAS DataBase Reference) | | NIST Chemistry Reference | 1H-Indole, 1-methyl-(603-76-9) | | EPA Substance Registry System | 1H-Indole, 1-methyl- (603-76-9) |
| 1-Methylindole Usage And Synthesis |
| Chemical Properties | deep yellow viscous liquid with a very unpleasant smell | | Uses | 1-Methylindole is useful for the determination of association constant for the electron-donor-acceptor complexes with 1-(2,4,6-trinitrophenyl) propan-2-one. It acts as a reactant for the preparation of polycyclic derivatives of indoles, bisindole derivatives and pharmaceutically active 2-oxo-1-pyrrolidine analogues. It is also used as a reactant for the preparation of Positron Emission Tomography (PET) imaging agents of protein kinase C (PKC) and glycogen synthase kinase-3 (GSK-3). | | Synthesis Reference(s) | Synthetic Communications, 26, p. 1349, 1996 DOI: 10.1080/00397919608003495Tetrahedron Letters, 27, p. 377, 1986 DOI: 10.1016/S0040-4039(00)84023-X | | General Description | 1-Methylindole undergoes Au(III)/TPPMS-catalyzed benzylation reaction with benzhydryl and benzylic alcohols. |
| 1-Methylindole Preparation Products And Raw materials |
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