Chlorohydroquinone

Chlorohydroquinone
  • CAS No.:615-67-8
Other grades of this product :
Chlorohydroquinone Basic information
Product Name:Chlorohydroquinone
Synonyms:2-CHLOROHYDROQUINONE: TECH., 90%;2-Chlorobenzene-1,4-diol;Chlorohydroquinone, 90%, tech.;Chlorohydroquinone,99%;Chlorohydroquinone, tech., 90% 5GR;Chlorohydroquinone (Technical Grade, ~90%);2-Chlorohydroquinone, tech. 90%, tech. 90%;Chlorohydroquinone technical grade, 85%
CAS:615-67-8
MF:C6H5ClO2
MW:144.56
EINECS:210-442-8
Product Categories:Dye Intermediate;Anthraquinones, Hydroquinones and Quinones
Mol File:615-67-8.mol
Chlorohydroquinone Chemical Properties
Melting point 100-104 °C (lit.)
Boiling point 263 °C (lit.)
density 1.2558 (rough estimate)
refractive index 1.4620 (estimate)
Fp 263°C
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka9.21±0.18(Predicted)
form Fine Crystalline Powder
color Light brown to gray
Water Solubility soluble
BRN 636835
CAS DataBase Reference615-67-8(CAS DataBase Reference)
NIST Chemistry Reference1,4-Benzenediol, 2-chloro-(615-67-8)
EPA Substance Registry SystemChlorohydroquinone (615-67-8)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 21-36/37/38-43
Safety Statements 36/37-37/39-26
RIDADR UN2811
WGK Germany 3
RTECS MX4800000
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29081990
Hazardous Substances Data615-67-8(Hazardous Substances Data)
ToxicityAn antidiarrhea drug used extensively in Japan. It has been shown to be the cause of subacute myelooptic neuropathy, a syndrome in which stiffness of the joints is accompanied by damage to the optic nerve.
MSDS Information
ProviderLanguage
2-Chloro-1,4-dihydroxybenzene English
ACROS English
SigmaAldrich English
ALFA English
Chlorohydroquinone Usage And Synthesis
Chemical Propertieslight brown to grey fine crystalline powder. It precipitates leafy crystals from chloroform and needle-like crystals from toluene. Freely soluble in water and alcohol, slightly soluble in ether and hot chloroform.
UsesChlorohydroquinone is a component of polyethers based on organotin with potential application to breast cancer treatment via growth inhibition. Also a component in the synthesis of contraceptive agents in pharmaceutical compounds. It is also used within hydroxylation and catalysis organic reactions in the synthesis of pharmacologically active phenolic compounds.
PreparationChlorohydroquinone is obtained by reacting p-benzoquinone with hydrochloric acid. First dissolve p-benzoquinone with chloroform and pass dry hydrogen chloride gas under cooling to obtain.
ApplicationChlorohydroquinone is a benzenediol that consists of hydroquinone bearing a single chloro substituent. It has a role as a metabolite. It is a member of monochlorobenzenes and a member of chlorohydroquinones. Chlorohydroquinone is used in photographic developing solutions. It is also a bactericide.
DefinitionChEBI: Chlorohydroquinone is a benzenediol that consists of hydroquinone bearing a single chloro substituent. It has a role as a metabolite. It is a member of monochlorobenzenes and a member of chlorohydroquinones.
Safety ProfilePoison by ingestion and intraperitoneal routes. Moderately toxic by skin contact. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORIDES.
Purification MethodsCrystallise the hydroquinone from CHCl3 or toluene. [Beilstein 6 IV 5767.]

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