Other grades of this product :
| 5-Nitroindole Basic information |
| 5-Nitroindole Chemical Properties |
| Melting point | 140-142 °C (lit.) | | Boiling point | 288.82°C (rough estimate) | | density | 1.3264 (rough estimate) | | refractive index | 1.5770 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Dichloromethane, Ethyl Acetate, Methanol | | form | Crystalline Powder or Needles | | pka | 15.25±0.30(Predicted) | | color | Yellow | | BRN | 383777 | | InChIKey | OZFPSOBLQZPIAV-UHFFFAOYSA-N | | CAS DataBase Reference | 6146-52-7(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-41 | | Safety Statements | 26-39-45-36/37 | | WGK Germany | 3 | | RTECS | NM1168200 | | F | 8 | | Hazard Note | Irritant | | HazardClass | IRRITANT, IRRITANT-HARMFUL | | HS Code | 29339900 |
| 5-Nitroindole Usage And Synthesis |
| Chemical Properties | Yellow-Green Cyrstalline Solid | | Uses | Reactant for preparation of:• ;Pharmaceutically active 2-oxo-1-pyrrolidine analogues1• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Protein Kinase Inhibitors and antiproliferative agents3• ;Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)4• ;Antifungal agents5• ;Cannabinoid receptor type 1 (CB1) antagonists6• ;Potential anticancer agents7• ;Potential antivascular agents8• ;Selective Anti-leukemic agents9• ;Anti human immunodeficiency virus subtype 1 ( | | Uses | 5-Nitroindole (cas# 6146-52-7) is a compound useful in organic synthesis. | | Uses | Reactant for preparation of:- Pharmaceutically active 2-oxo-1-pyrrolidine analogues
- Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Protein Kinase Inhibitors and antiproliferative agents
- Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)
- Antifungal agents
- Cannabinoid receptor type 1 (CB1) antagonists
- Potential anticancer agents
- Potential antivascular agents
- Selective Anti-leukemic agents
- Anti human immunodeficiency virus subtype 1 (HIV-1) agents
| | Purification Methods | Decolourise (charcoal) 5-nitroindole and recrystallise it twice from aqueous EtOH or recrystallise it from octane. It has UV: 265 and 324nm (EtOH). [Beilstein 20 III/IV 3194, 20/7 V 41.] |
| 5-Nitroindole Preparation Products And Raw materials |
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