Other grades of this product :
| 6-Fluoroindole Basic information |
| 6-Fluoroindole Chemical Properties |
| Melting point | 72-76 °C (lit.) | | Boiling point | 230°C (rough estimate) | | density | 1.1203 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | Crystalline Powder | | pka | 16.40±0.30(Predicted) | | color | Beige-brown | | Water Solubility | Insoluble | | Sensitive | Light Sensitive | | BRN | 112192 | | CAS DataBase Reference | 399-51-9(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | F | 10 | | HazardClass | IRRITANT | | HS Code | 29339900 |
| 6-Fluoroindole Usage And Synthesis |
| Chemical Properties | beige-brown crystalline powder | | Uses | 6-Fluoroindole acts as a reagent in the synthesis of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, which acts as a potential anticancer immunomodulator. It is also employed as an antifungal and antibacterial agent. Further, it serves as a potent selective serotonin reuptake inhibitor. In addition to this, it is used as a inhibitor of HIV-1 attachment. | | General Description | 6-Fluoroindole is a halogen substituted indole. Experimental ionization potential of 6-fluoroindole has been evaluated. Preparation of 6-fluoroindole via nitration of indoline has been reported. |
| 6-Fluoroindole Preparation Products And Raw materials |
| Raw materials | Ethenamine, 2-(4-fluoro-2-nitrophenyl)-N,N-dimethyl-, (1E)--->1H-Indole,6-fluoro-1-hydroxy-(9CI)-->Benzenamine, 2-ethynyl-5-fluoro- (9CI)-->6-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-->5-CHLORO-6-FLUOROINDOLE-->Ethyl 6-fluoroindole-2-carboxylate-->6-Fluoroindole-2-carboxylic acid-->4-Fluoro-2-nitrotoluene-->N,N-Dimethylformamide dimethyl acetal | | Preparation Products | 1H-Indole, 6-fluoro-4-iodo--->6-FLUOROINDOLE-3-ACETIC ACID-->(E)-3-(2-(1H-tetrazol-5-yl)vinyl)-6-fluoro-1H-indole-->6-FLUORO-1H-INDOLE-3-CARBOXYLIC ACID-->Indole-6-boronic acid pinacol ester-->6-Fluoro-2-oxindole |
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