| N-Carbobenzyloxy-L-alanine Basic information |
| Product Name: | N-Carbobenzyloxy-L-alanine |
| Synonyms: | N-CBZ-L-ALANINE;N-CBZ-L-ALANINE-OH;N-CARBOBENZYLOXY-L-ALANINE;N-ALPHA-BENZYLOXYCARBONYL-L-ALANINE;N-ALPHA-CARBOBENZOXY-L-ALANINE;N-ALPHA-CBZ-L-ALANINE;N-BENZYLOXYCARBONYL-L-ALANINE;N-CARBOBENZOXY-L-ALANINE |
| CAS: | 1142-20-7 |
| MF: | C11H13NO4 |
| MW: | 223.23 |
| EINECS: | 214-532-8 |
| Product Categories: | Alanine [Ala, A];Z-Amino Acids and Derivatives;Amino Acids;Amino Acids (N-Protected);Biochemistry;Cbz-Amino Acids;Protected Amino Acids;PROTECTED AMINO ACID & PEPTIDES;Chiral Compounds;Z-Amino acid series;bc0001 |
| Mol File: | 1142-20-7.mol |
| N-Carbobenzyloxy-L-alanine Chemical Properties |
| Melting point | 84-87 °C |
| alpha | -15 º (c=2, AcOH 24 ºC) |
| Boiling point | 364.51°C (rough estimate) |
| density | 1.2446 (rough estimate) |
| refractive index | -14.5 ° (C=2, AcOH) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 4.00±0.10(Predicted) |
| form | Powder |
| color | White |
| optical activity | [α]23/D 14.2°, c = 2 in acetic acid |
| BRN | 2056164 |
| InChIKey | TYRGLVWXHJRKMT-QMMMGPOBSA-N |
| CAS DataBase Reference | 1142-20-7(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29242990 |
| MSDS Information |
| Provider | Language |
|---|---|
| N-CBZ-L-Alanine | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| N-Carbobenzyloxy-L-alanine Usage And Synthesis |
| Chemical Properties | white powder |
| Uses | N-Benzyloxycarbonyl-L-alanine is an intermediate in the synthesis of Perindopril (P287500), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive. |
| N-Carbobenzyloxy-L-alanine Preparation Products And Raw materials |
| Preparation Products | DELAPRIL-->N-Cbz-D-Alanine-->(S)-4-Methyl-2,5-oxazolidonedione |
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