3-Nitro-L-tyrosine

CAS No.：621-44-3

Other grades of this product :

3-Nitro-L-tyrosine Basic information

Product Name:	3-Nitro-L-tyrosine
Synonyms:	(2R)-2-Amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid;L-Tyrosine, 3-nitro-;3-Nitro-L-tyrosine,99%;(S)-2-aMino-3-(4-hydroxy-3-nitrophenyl)propanoic acid;Z-D-Dap(Boc);3-NITRO-L-TYROSINE (RING-13C6);(S)-3-(3-Nitro-4-hydroxyphenyl)alanine;3-Nitro-L-tyrosine≥ 98% (Assay)
CAS:	621-44-3
MF:	C9H10N2O5
MW:	226.19
EINECS:	210-688-6
Product Categories:	Pharmaceutical Raw Materials;Amino Acids;Tyrosine [Tyr, Y];Unusual Amino Acids;Oxidative Stress Proteins and ReagentsPeptide Synthesis;Cell Stress;Peptide Synthesis;Tyrosine Derivatives;Unnatural Amino Acid Derivatives;Nitric Oxide and Cell Stress;Amino Acids & Derivatives;Aromatics
Mol File:	621-44-3.mol

3-Nitro-L-tyrosine Chemical Properties

Melting point	233-235 °C (dec.) (lit.)
alpha	4 º (c=1, 1N HCl)
Boiling point	367.79°C (rough estimate)
density	1.4160 (rough estimate)
refractive index	1.5373 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Aqueous Acid (Slightly), Water
pka	2.17±0.20(Predicted)
form	crystalline
color	yellow to green
Water Solubility	insoluble
BRN	2813157
CAS DataBase Reference	621-44-3(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	24/25-37/39-26-36
WGK Germany	3
HS Code	29225090

MSDS Information

Provider	Language
3-Nitro-L-tyrosine	English
SigmaAldrich	English
ACROS	English
ALFA	English

3-Nitro-L-tyrosine Usage And Synthesis

Description	Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo. Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions. The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by gas chromatography/mass spectrometry.
Chemical Properties	ochre-yellow to yellow-green powder
Uses	A marker for peroxynitrite. Oxidant and cytotoxic agent.
Uses	3-Nitro-L-tyrosine is used as an indicator of the formation of peroxynitrite by NO-dependent oxidative damage.
Biochem/physiol Actions	Oxidant and cytotoxic agent.

3-Nitro-L-tyrosine Preparation Products And Raw materials

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