Grela 2nd Generation

Grela 2nd Generation
  • CAS No.:502964-52-5

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
Grela 2nd Generation Basic information
Reaction
Product Name:Grela 2nd Generation
Synonyms:RutheniuM, [1,3-bis(2,4,6-triMethylphenyl)-2-iMidazolidinylidene]dichloro[[2-(1-Methylethoxy-κO)-5-nitrophenyl]Methylene-κC]-, (SP-5-41)-;[1,3-bis (2,4,6-trimethylphenyl) -2- imidazolidinylidene] (2-isopropoxy-5-nitrophenyl methylene) ruthenium dichloride;nitro-Grela;(SP-5-41)-[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro[[2-(1-methylethoxy-kO)-5-nitrophenyl]Methylene-kC]-ruthenium;Grela nitro-Grela;1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichloro-[(5-nitro-2-propan-2-yloxyphenyl)methylidene]ruthenium;Grela's catalyst;Grela 2
CAS:502964-52-5
MF:C31H36Cl2N3O3Ru
MW:670.62
EINECS:
Product Categories:
Mol File:502964-52-5.mol
Grela 2nd Generation Chemical Properties
Melting point >300 °C
storage temp. 2-8°C
form Powder
color green
CAS DataBase Reference502964-52-5
Safety Information
MSDS Information
Grela 2nd Generation Usage And Synthesis
Reaction
  1. This catalyst is used for an efficient synthesis of HCV Protease Inhibitor, BILN 2061.
  2. The nitro-Grela catalyst is a stable olefin metathesis initiator active in various ring-closing, cross, and enyne metathesis reactions. Its efficiency has been proven in numerous total syntheses of natural and biologically active compounds, and in material science.
Usesnitro-Grela is a universal catalyst which provides good results in a wide spectrum of olefin metathesis transformations. The catalyst provides high efficiency in cross metathesis (CM) reactions between type 1 olefins and an electron deficient partner. The catalyst is very good for CM of disubstituted internal olefins.
Grela 2nd Generation Preparation Products And Raw materials

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