| FORMAMIDOXIME Basic information |
| Product Name: | FORMAMIDOXIME |
| Synonyms: | formamideoxime;formamidoxim;isuretin;n-hydroxy-methanimidamid;n-hydroxymethanimidamide;FORMAMIDOXIME;isouretin;Formamidoxim [German] |
| CAS: | 624-82-8 |
| MF: | CH4N2O |
| MW: | 60.06 |
| EINECS: | 210-865-8 |
| Product Categories: | pharmacetical;Imines/Amidines;Nitrogen Compounds;Organic Building Blocks |
| Mol File: | 624-82-8.mol |
| FORMAMIDOXIME Chemical Properties |
| Melting point | 112-115 °C(lit.) |
| Boiling point | 95.06°C (rough estimate) |
| density | 1.3000 (rough estimate) |
| refractive index | 1.4840 (estimate) |
| storage temp. | 2-8°C |
| pka | 14.53±0.40(Predicted) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-40 |
| Safety Statements | 22-36 |
| WGK Germany | 3 |
| RTECS | LQ4632000 |
| HazardClass | IRRITANT |
| HS Code | 2928009090 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| FORMAMIDOXIME Usage And Synthesis |
| Uses | Formamidoxime may be used as inhibitor of DNA synthesis. |
| Biochem/physiol Actions | Formamidoxime undergoes oxidative cleavage of C==N bonds in tracheal smooth muscle cells catalyzed by liver cytochrome P450 producing NO. It inhibits replicative DNA synthesis. It has antitumor activity against L1210 leukemia. |
| FORMAMIDOXIME Preparation Products And Raw materials |
| Raw materials | Methanimidic acid, N-hydroxy-, ethyl ester-->ETHYL FORMIMIDATE HYDROCHLORIDE-->Diethyl ether-->POTASSIUM CYANIDE-->Water-->HYDROXYLAMINE-->Ethanol-->HYDROGEN CYANIDE |
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