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| Mal-PEG2-NHS ester Basic information |
| Product Name: | Mal-PEG2-NHS ester | | Synonyms: | Mal-PEG2-NHS ester;2,5-dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate;Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester;Mal-PEG2-Osu;2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate | | CAS: | 1433997-01-3 | | MF: | C15H18N2O8 | | MW: | 354.31 | | EINECS: | | Product Categories: | ADCs Linkers;peg | | Mol File: | 1433997-01-3.mol |
| Mal-PEG2-NHS ester Chemical Properties |
| Boiling point | 524.3±60.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | solubility | Soluble in DCM | | pka | -2.34±0.20(Predicted) |
| Mal-PEG2-NHS ester Usage And Synthesis |
| Description | Mal-PEG2-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | | Uses | Mal-?PEG2-?NHS Ester is a reagent used in the preparation of antibody-drug conjugates that bind to human-antigen targets in the effort to combat cancers. |
| Mal-PEG2-NHS ester Preparation Products And Raw materials |
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