Other grades of this product :
| ETHYLTHIOUREA Basic information |
| ETHYLTHIOUREA Chemical Properties |
| Melting point | 108-110 °C(lit.) | | Boiling point | 132 °C | | density | 1.055 (estimate) | | refractive index | 1.5500 (estimate) | | storage temp. | Store at RT | | solubility | methanol: soluble25mg/mL, clear, colorless | | pka | 14.97±0.29(Predicted) | | Water Solubility | Soluble in water (24g/L). | | BRN | 1699551 | | InChIKey | GMEHFXXZSWDEDB-UHFFFAOYSA-N | | CAS DataBase Reference | 625-53-6(CAS DataBase Reference) | | EPA Substance Registry System | Ethylthiourea (625-53-6) |
| ETHYLTHIOUREA Usage And Synthesis |
| Uses | N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides | | General Description | N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described. | | Biological Activity | Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). | | Safety Profile | Poison by ingestion.
SYN: 1-ETHYLTHIOUREA
Experimental teratogenic effects. Mutation
data reported. When heated to decomposition it emits toxic fumes of Sox and NOx. | | Purification Methods | Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.] |
| ETHYLTHIOUREA Preparation Products And Raw materials |
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