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| (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Basic information |
| (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Chemical Properties |
| Boiling point | 133 °C/10 mmHg (lit.) | | alpha | +66°(23℃, c=1.15, CHCl3) | | density | 1.309 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.467(lit.) | | Fp | >230 °F | | storage temp. | 2-8°C | | form | clear liquid | | pka | 13.07±0.20(Predicted) | | Specific Gravity | 1.32 | | color | Colorless to Light yellow | | optical activity | [α]23/D +66°, c = 1.15 in chloroform | | BRN | 80588 | | CAS DataBase Reference | 56881-90-4(CAS DataBase Reference) |
| WGK Germany | 3 | | HS Code | 2932209090 |
| (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Usage And Synthesis |
| Uses | (R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize: - δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions.
- Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents.
- Botryolide B via esterification and ring-closing metathesis reaction.
- Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists.
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| (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Preparation Products And Raw materials |
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