(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE

(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
  • CAS No.:56881-90-4

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Basic information
Product Name:(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Synonyms:2(3H)-FURANONE, DIHYDRO-3-HYDROXY-, (R);(R)-(+)-α-Hydroxy-γ-butyrolactone;(r)-4,5-dihydro-3-hydroxy-2(3h)-furanone;(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE 98+%;RARECHEM AK HZ 0027;(R)-(+)-DIHYDRO-3-HYDROXY-2(3H)-FURANONE;(R)-2-HYDROXYBUTYROLACTONE;(R)-2-HYDROXY-GAMMA-BUTYROLACTONE
CAS:56881-90-4
MF:C4H6O3
MW:102.09
EINECS:
Product Categories:Chiral Building Blocks;Simple Alcohols (Chiral);Small molecule;Synthetic Organic Chemistry
Mol File:56881-90-4.mol
(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Chemical Properties
Boiling point 133 °C/10 mmHg (lit.)
alpha +66°(23℃, c=1.15, CHCl3)
density 1.309 g/mL at 25 °C (lit.)
refractive index n20/D 1.467(lit.)
Fp >230 °F
storage temp. 2-8°C
form clear liquid
pka13.07±0.20(Predicted)
Specific Gravity1.32
color Colorless to Light yellow
optical activity[α]23/D +66°, c = 1.15 in chloroform
BRN 80588
CAS DataBase Reference56881-90-4(CAS DataBase Reference)
Safety Information
WGK Germany 3
HS Code 2932209090
MSDS Information
ProviderLanguage
SigmaAldrich English
(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Usage And Synthesis
Uses(R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize:
  • δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions.
  • Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents.
  • Botryolide B via esterification and ring-closing metathesis reaction.
  • Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists.
(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Preparation Products And Raw materials

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