Product

L-Glutamic acid 5-methyl ester

CAS No.：1499-55-4

Other grades of this product :

L-Glutamic acid 5-methyl ester Basic information

Product Name:	L-Glutamic acid 5-methyl ester
Synonyms:	L-GlutaMic acid 5-Methyl ester, 95+%;L-Glutamic acid 5-methyl ester 99%;L-Glutamic acid γ-methyl ester≥ 98.5% (HPLC);Glu(Ome)-OH;(5)-methyl L-hydrogen glutamate;L-GUTAMIC ACID 5-METHYL ESTER 99%;L-Gutamic Acid 5-Methyl Ester;Mono-methyl-L-glutamate
CAS:	1499-55-4
MF:	C6H11NO4
MW:	161.16
EINECS:	216-110-9
Product Categories:	Pyrazoles;Glutamic acid [Glu, E];Amino Acids Derivatives;Amino Acids and Derivatives
Mol File:	1499-55-4.mol

L-Glutamic acid 5-methyl ester Chemical Properties

Melting point	182 °C (dec.) (lit.)
alpha	13 º (c=1, H2O 24 ºC)
Boiling point	287.44°C (rough estimate)
density	1.3482 (rough estimate)
refractive index	29 ° (C=2, 6mol/L HCl)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Water Solubility	Soluble in water
pka	2.18±0.10(Predicted)
form	powder to crystal
color	White to Almost white
optical activity	[α]20/D +29°, c = 2 in 6 M HCl
BRN	1725252
CAS DataBase Reference	1499-55-4(CAS DataBase Reference)

Safety Information

Safety Statements	24/25
WGK Germany	3
HS Code	29224999

MSDS Information

Provider	Language
L-Glutamic acid gamma-methyl ester	English
SigmaAldrich	English
ACROS	English
ALFA	English

L-Glutamic acid 5-methyl ester Usage And Synthesis

Chemical Properties

white amorphous powder

Uses

L-Glutamic acid 5-methyl ester is a protected form of L-Glutamic acid (G596960). L-Glutamic acid is a nonessential amino acid that is important to the mammalian central nervous system. L-Glutamic acid is also a neurotransmitter for cone photoreceptors in the human brain and is used as a treatment for patients who have liver disease accompanied by encephalopathy (a condition termed ‘hepatic coma’).

L-Glutamic acid 5-methyl ester Preparation Products And Raw materials

Raw materials	Methanol-->Diethyl ether-->Thionyl chloride-->Ammonium hydroxide-->L-Glutamic acid
Preparation Products	L-Glutamine-->Aceglutamide-->L-Glutamic acid dimethyl ester hydrochloride-->H-Glu(OMe)-OtBu-->BOC-GLU(OME)-OH

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