4-Aminobenzotrifluoride

4-Aminobenzotrifluoride
  • CAS No.:455-14-1

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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4-Aminobenzotrifluoride Basic information
Product Name:4-Aminobenzotrifluoride
Synonyms:TIMTEC-BB SBB003956;P-(TRIFLUOROMETHYL)ANILINE;P-AMINOBENZOTRIFLUORIDE;1-AMINO-4-(TRIFLUOROMETHYL)BENZENE;4-(TRIFLUOROMETHYL)ANILINE;4-AMINOBENZOTRIFLUORIDE;4-AMINO-A,A,A-TRIFLUOROTOLUENE;A,A,A-TRIFLUORO-P-TOLUIDINE
CAS:455-14-1
MF:C7H6F3N
MW:161.12
EINECS:207-236-5
Product Categories:API intermediates;Fluorochemicals;Anilines, Aromatic Amines and Nitro Compounds;Pharmaceutical Intermediate;Amines;amine;Aromatics;Mutagenesis Research Chemicals;bc0001
Mol File:455-14-1.mol
4-Aminobenzotrifluoride Chemical Properties
Melting point 3-8 °C
Boiling point 83 °C12 mm Hg(lit.)
density 1.283 g/mL at 25 °C(lit.)
refractive index n20/D 1.483(lit.)
Fp 188 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
form Liquid
pka2.45(at 25℃)
Specific Gravity1.283
color Clear colorless to yellow
Water Solubility <0.1 g/100 mL
Sensitive Air Sensitive
BRN 1564853
InChIKeyODGIMMLDVSWADK-UHFFFAOYSA-N
LogP1.95 at 20℃
CAS DataBase Reference455-14-1(CAS DataBase Reference)
NIST Chemistry ReferenceBenzenamine, 4-(trifluoromethyl)-(455-14-1)
EPA Substance Registry System4-(Trifluoromethyl)aniline (455-14-1)
Safety Information
Hazard Codes T,N,Xi,Xn
Risk Statements 25-36-50/53-36/37/38-33-20/21/22
Safety Statements 26-45-60-61-36/37/39-36
RIDADR UN 2810 6.1/PG 3
WGK Germany 3
RTECS XU9260000
Hazard Note Toxic/Irritant
TSCA T
HazardClass 6.1
PackingGroup III
HS Code 29214300
MSDS Information
ProviderLanguage
4-(Trifluoromethyl)aniline English
SigmaAldrich English
ACROS English
ALFA English
4-Aminobenzotrifluoride Usage And Synthesis
Chemical Propertiesclear colorless to yellow liquid
Uses4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis.
Uses4-(Trifluoromethyl)aniline was used in the synthesis of 4-(trialkylmethyl)anilines. It was also used as a synthetic building block.
DefinitionChEBI: A substituted aniline that is a benzene ring substituted with an amino group at position 1 and a trifluoromethyl group at position 4.
Synthesis Reference(s)The Journal of Organic Chemistry, 54, p. 2873, 1989 DOI: 10.1021/jo00273a020
General DescriptionPharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

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