| P-TOLUENESULFONYL FLUORIDE Basic information |
| Product Name: | P-TOLUENESULFONYL FLUORIDE |
| Synonyms: | 4-TOLUENESULPHONYL FLUORIDE;4-TOLUENESULFONYL FLUORIDE;4-METHYLBENZENESULFONYL FLUORIDE;P-TOLUENESULFONYL FLUORIDE;P-TOLUENESULPHONYL FLUORIDE;TOSYL FLUORIDE;4-methyl-benzenesulfonylfluorid;p-Fluorosulfonyltoluene |
| CAS: | 455-16-3 |
| MF: | C7H7FO2S |
| MW: | 174.19 |
| EINECS: | 207-238-6 |
| Product Categories: | Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds |
| Mol File: | 455-16-3.mol |
| P-TOLUENESULFONYL FLUORIDE Chemical Properties |
| Melting point | 41-42 °C(lit.) |
| Boiling point | 112 °C16 mm Hg(lit.) |
| density | 1.2768 (estimate) |
| Fp | 222 °F |
| Water Solubility | Hydrolyzes in water. |
| Sensitive | Moisture Sensitive |
| BRN | 2208423 |
| Exposure limits | ACGIH: TWA 2.5 mg/m3NIOSH: IDLH 250 mg/m3 |
| CAS DataBase Reference | 455-16-3(CAS DataBase Reference) |
| EPA Substance Registry System | Benzenesulfonyl fluoride, 4-methyl- (455-16-3) |
| Safety Information |
| Hazard Codes | C |
| Risk Statements | 20/21/22-34 |
| Safety Statements | 22-26-27-36/37/39-45 |
| RIDADR | UN 3261 8/PG 2 |
| WGK Germany | 3 |
| RTECS | XT8050000 |
| Hazard Note | Corrosive |
| TSCA | T |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29049095 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| P-TOLUENESULFONYL FLUORIDE Usage And Synthesis |
| Chemical Properties | White to beige fused mass |
| Uses | p-Toluenesulfonyl fluoride is used for sulfonylation of organometallic reagents as a simple, one-step synthesis of sulfones. It is useful in the treatment of Alzheimer?s disease. It is used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation. |
| Uses | Protease inhibitor. |
| General Description | p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease. |
| P-TOLUENESULFONYL FLUORIDE Preparation Products And Raw materials |
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