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| Mafenide hydrochloride Basic information |
| Product Name: | Mafenide hydrochloride | | Synonyms: | masudin;morfanil;p-aminomethylphenylsulfonamidehydrochloride;sulfamylonhydrochloride;sulfbenzaminehydrochloride;MARFANIL;MARFANIL HYDROCHLORIDE;MAFENIDE HYDROCHLORIDE | | CAS: | 138-37-4 | | MF: | C7H11ClN2O2S | | MW: | 222.69 | | EINECS: | 205-325-3 | | Product Categories: | | Mol File: | 138-37-4.mol |
| Mafenide hydrochloride Chemical Properties |
| Melting point | 261-263 °C(lit.) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | neat | | color | White | | Merck | 13,5671 | | InChIKey | SIACJRVYIPXFKS-UHFFFAOYSA-N | | CAS DataBase Reference | 138-37-4(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 42/43 | | Safety Statements | 22-36/37-45 | | WGK Germany | 2 | | RTECS | XT5425000 | | HS Code | 29350090 | | Toxicity | LD50 in rats, mice (mg/kg): 1170, 900 i.v. (Skulan, Hoppe) |
| Mafenide hydrochloride Usage And Synthesis |
| Uses | Antibacterial;Inhibitor of folic acid biosynthesis | | Purification Methods | Crystallise the salt from dilute HCl or 95% EtOH and dry it in a vacuum at 100o. It is an antibacterial. [Miller et al. J Am Chem Soc 62 2099 1940, Bergeim & Barker J Am Chem Soc 66 1459 1944.] The sulfate salt has m 254-255o (from aqueous EtOH). [Beilstein 14 III 2223, 14 IV 2799.] |
| Mafenide hydrochloride Preparation Products And Raw materials |
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