DIETHYLENETRIAMINEPENTAACETIC DIANHYDRIDE

CAS No.：23911-26-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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DIETHYLENETRIAMINEPENTAACETIC DIANHYDRIDE Basic information

Product Name:	DIETHYLENETRIAMINEPENTAACETIC DIANHYDRIDE
Synonyms:	N,N-BIS[2-(2,6-DIOXOMORPHOLINO)ETHYL]GLYCINE;DIETHYLENETRIAMINEPENTAACETIC ACID ANHYDRIDE;DIETHYLENETRIAMINEPENTAACETIC ANHYDRIDE;DIETHYLENETRIAMINEPENTAACETIC DIANHYDRIDE;DIETHYLENETRIAMINE-N,N,N',N'',N''-PENTAACETIC ACID ANHYDRIDE;DIETHYLENETRIAMINEPENTAACETIC ACID DIANHYDRIDE;DTPA ANHYDRIDE;DTPA DIANHYDRIDE
CAS:	23911-26-4
MF:	C14H19N3O8
MW:	357.32
EINECS:
Product Categories:	proteinmod;Analytical Chemistry;Chelating Reagents;Complexones;EDTA Analogs;Ligands for Pharmaceutical Research;Magnetic Resonance Imaging (Chelating Reagents)
Mol File:	23911-26-4.mol

DIETHYLENETRIAMINEPENTAACETIC DIANHYDRIDE Chemical Properties

Melting point	182-184 °C (lit.)
Boiling point	656.2±55.0 °C(Predicted)
density	1.460±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	-20°C
form	powder to crystal
pka	2.19±0.10(Predicted)
color	White to Light yellow to Light orange
Water Solubility	Hydrolyzes in water.
Sensitive	Moisture Sensitive
BRN	1230954
CAS DataBase Reference	23911-26-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
F	10-21
HS Code	29224999

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

DIETHYLENETRIAMINEPENTAACETIC DIANHYDRIDE Usage And Synthesis

Uses

NSC 379317 or DTPAA is a useful synthetic intermediate in producing DPTA, in which it is used to synthesize the GO-DEN(Gd-DTPA)-mAb, a contrast reagent for prostate tumor MRI imaging. GO-DEN(Gd-DTPA)-mAb can be coupled with DOX to produce GO-DEN(Gd-DTPA)-mAb/DOX, creating an effective delivery of anti cancer drugs to the prostate cancer cells, PC-3, in mice.

DIETHYLENETRIAMINEPENTAACETIC DIANHYDRIDE Preparation Products And Raw materials

Raw materials

Diethylenetriaminepentaacetic acid

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