TETRAETHYL 1,1,2,2-ETHANETETRACARBOXYLATE

CAS No.：632-56-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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TETRAETHYL 1,1,2,2-ETHANETETRACARBOXYLATE Basic information

Product Name:	TETRAETHYL 1,1,2,2-ETHANETETRACARBOXYLATE
Synonyms:	1,1,2,2-Ethanetetracarboxylic acid, tetraethyl ester;1,1,2,2-Tetracarbethoxyethane;ethane-1,1,2,2-tetracarboxylicacidtetraethylester;Tetrakis(ethoxycarbonyl)ethane;TETRAETHYL 1,1,2,2-ETHANETETRACARBOXYLATE;tetraethyl ethane-1,1,2,2-tetracarboxylate;ETHYL ETHANETETRACARBOXYLATE;Tetraethyl-1,1,2,2-ethanetetracarboxylate 97%
CAS:	632-56-4
MF:	C14H22O8
MW:	318.32
EINECS:	211-180-7
Product Categories:	Building Blocks;C12 to C63;C12 to C63;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Carbonyl Compounds;Esters
Mol File:	632-56-4.mol

TETRAETHYL 1,1,2,2-ETHANETETRACARBOXYLATE Chemical Properties

Melting point	73-75 °C (lit.)
Boiling point	377.49°C (rough estimate)
density	1.0640
refractive index	1.4105 (estimate)
pka	10.58±0.59(Predicted)
BRN	1805842

Safety Information

Safety Statements	22-24/25
WGK Germany	3

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

TETRAETHYL 1,1,2,2-ETHANETETRACARBOXYLATE Usage And Synthesis

Chemical Properties	WHITE CRYSTALLINE NEEDLES
Uses	Tetraethyl 1,1,2,2-ethanetetracarboxylate was used in the synthesis of double-ring molecules. It was also used in the preparation of tapt and tapt·4HCl·EtOH·0.5H₂O.
Purification Methods	Recrystallise the ester twice from EtOH by cooling to 0o. [Mochizuki et al. Bull Chem Soc Jpn 64 1750 1991, Weinges et al. Angew Chem 93 1008 1981, Beilstein 2 IV 2415.]

TETRAETHYL 1,1,2,2-ETHANETETRACARBOXYLATE Preparation Products And Raw materials

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