1-Chloro-4-iodobenzene

1-Chloro-4-iodobenzene
  • CAS No.:637-87-6
Other grades of this product :
1-Chloro-4-iodobenzene Basic information
Product Name:1-Chloro-4-iodobenzene
Synonyms:1-Chloro-4-iodobenzene, 97+%;Chloro-4-iodobenz;P-IODOCHLOROBENZENE;P-CHLOROIODOBENZENE;1-chloro-4-iodo-benzen;4-Chlorophenyl iodide;1-Chloro-4-iodobenze;1-Chloro-4-iodobenzene, 99% 25GR
CAS:637-87-6
MF:C6H4ClI
MW:238.45
EINECS:211-305-5
Product Categories:Chlorine Compounds;Iodine Compounds;White to light yellowcrystalline powder;Aryl;C6;Halogenated Hydrocarbons
Mol File:637-87-6.mol
1-Chloro-4-iodobenzene Chemical Properties
Melting point 53-54 °C(lit.)
Boiling point 226-227 °C(lit.)
density 1.8860
Fp 227 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly, Heated), Methanol (Slightly, Heated)
form Crystalline Powder or Crystals
color Off-white to light beige
Sensitive Light Sensitive
BRN 1634414
InChIKeyGWQSENYKCGJTRI-UHFFFAOYSA-N
CAS DataBase Reference637-87-6(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, 1-chloro-4-iodo-(637-87-6)
EPA Substance Registry SystemBenzene, 1-chloro-4-iodo- (637-87-6)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 36/37-24/25
WGK Germany 3
TSCA T
HazardClass IRRITANT
HS Code 29039990
MSDS Information
ProviderLanguage
1-Chloro-4-iodobenzene English
ACROS English
SigmaAldrich English
ALFA English
1-Chloro-4-iodobenzene Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Usessuzuki reaction
Uses4-Chloroiodobenzene is used as a reagent in the synthesis of Clothiapine (C588550); an atypical antipsychotic of the dibenzothiazepine chemical class that has shown efficacy in treatment-resistant schizophrenic patients.
Purification MethodsDistil it in a vacuum then recrystallise it from EtOH. [Sugden J Chem Soc 1173 1924, Beilstein 5 H 221, 5 III 579, 5 IV 695.]

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