Other grades of this product :
| Selank peptide Basic information |
| Product Name: | Selank peptide | | Synonyms: | Selank peptide;SelankAcetate;PL14736;L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline;L-THREONYL-L-LYSYL-L-PROLYL-L-ARGINYL-L-PROLYLGLYCYL-L-PROLINE; MONOACETATE;H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH;SLANK;Selank peptid | | CAS: | 129954-34-3 | | MF: | C33H57N11O9 | | MW: | 751.87 | | EINECS: | 232-660-2 | | Product Categories: | | Mol File: | 129954-34-3.mol |
| Selank peptide Chemical Properties |
| Melting point | 134-136 °C | | density | 1.53±0.1 g/cm3(Predicted) | | pka | 3.43±0.20(Predicted) |
| Selank peptide Usage And Synthesis |
| Description | Selank is a synthetic derivative of the tetrapeptide tuftsin that contains a proline-glycine-proline sequence at the C-terminus and has anxiolytic and anti-inflammatory activities. It increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region when used at a concentration of 1 μM. It decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test. It increases locomotor activity of high-anxiety Balb/c, but not C57Bl/6, mice in the open field test. Selank (0.01 mg/kg) decreases verticalization induced by apomorphine in mice. It also decreases expression of the inflammation-related genes Il2rg and Xcr1 in mouse spleen after 90 minutes when administered at a dose of 100 μg/kg. |
| Selank peptide Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye