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| Boc-6-AMinocaproic acid Basic information |
| Product Name: | Boc-6-AMinocaproic acid | | Synonyms: | Boc-6-Ahx-OH ,98.5%(HPLC);Boc-6-Ahx-OH,6-(Boc-amino)caproic acid, 6-(Boc-amino)hexanoic acid, Boc-6-aminohexanoic acid;Boc-6-Ahx-OH(Boc-6-aMinohexanoic acid);Boc-ε- AMinocaproic acid Boc-ε- AMinocaproic acid;6-[N-(tert-Butoxycarbonyl)aMino]caproic Acid;N-(tert-Butoxycarbonyl)-ε-aMinocaproic Acid;N-(tert-Butoxycarbonyl)-ε-aMinohexanoic Acid;N-(tert-Butyloxycarbonyl)-ε-aMinocaproic Acid | | CAS: | 6404-29-1 | | MF: | C11H21NO4 | | MW: | 231.29 | | EINECS: | | Product Categories: | Amino Acid Derivatives;Aliphatics;Amino Acids;Unusual Amino Acids;Amines | | Mol File: | 6404-29-1.mol |
| Boc-6-AMinocaproic acid Chemical Properties |
| Melting point | 35-40 °C | | Boiling point | 166°C/0.3mmHg(lit.) | | density | 1.065±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Chloroform, Ethyl Acetate | | pka | 4.76±0.10(Predicted) | | form | Powder | | color | White | | Water Solubility | Soluble in chloroform and ethyl acetate. Slightly soluble in water. | | BRN | 2049561 | | CAS DataBase Reference | 6404-29-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-24/25-26 | | WGK Germany | 3 | | F | 21 | | HazardClass | IRRITANT | | HS Code | 29241990 |
| Boc-6-AMinocaproic acid Usage And Synthesis |
| Description | Boc-6-aminohexanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | | Chemical Properties | Colorless crystal | | Uses | 6-(Boc-amino)hexanoic acid is used in the preparation of esters of 6-aminohexanoic acid as antibacterial agents. EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carboxy peptidase, plasmin, and plasminogen activator. | | Uses | Protected ε-Aminocaproic Acid (A603015), Boc-6-AMinocaproic acid can be used in the preparatiom of esters of 6-aminohexanoic acid.
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| Boc-6-AMinocaproic acid Preparation Products And Raw materials |
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