Forchlorfenuron

Forchlorfenuron
  • CAS No.:68157-60-8
Other grades of this product :
Forchlorfenuron Basic information
Product Name:Forchlorfenuron
Synonyms:CPPU;KT-30;FORCHLORFENURON;4-CPPU;1-(2-CHLORO-4-PYRIDYL)-3-PHENYLUREA;1-(2-CHLOROPYRIDIN-4-YL)-3-PHENYL-UREA;4pu30;cn11-3138
CAS:68157-60-8
MF:C12H10ClN3O
MW:247.68
EINECS:614-346-0
Product Categories:plantgrowth;Agro-Products;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;FINE Chemical & INTERMEDIATES;PLANT GROWTH REGULATOR;Biochemistry;Chloropyridines;Cytokinins;Halopyridines;Plant Growth Regulators;Plant Hormones
Mol File:68157-60-8.mol
Forchlorfenuron Chemical Properties
Melting point 170-172°C
Boiling point 308.4±27.0 °C(Predicted)
density 1.415±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility Soluble in DMSO or Ethanol
pka12.55±0.70(Predicted)
form neat
color White or off-white
Stability:Stable for 1 year from date ofpurchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKeyGPXLRLUVLMHHIK-UHFFFAOYSA-N
CAS DataBase Reference68157-60-8(CAS DataBase Reference)
EPA Substance Registry SystemForchlorfenuron (68157-60-8)
Safety Information
Hazard Codes Xi,N,Xn
Risk Statements 36/37-51/53-40
Safety Statements 26-36-61-46-36/37
RIDADR UN3077 9/PG 3
WGK Germany 3
RTECS YS7182500
HazardClass 9
PackingGroup III
HS Code 29333990
Hazardous Substances Data68157-60-8(Hazardous Substances Data)
ToxicityLD50 oral in mouse: > 500mg/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
Forchlorfenuron Usage And Synthesis
DescriptionForchlorfenuron (68157-60-8) reversibly perturbs mammalian septin assembly, organization and function.? Has no effect on actin or tubulin polymerization.1,2 FCF induces effects on mitosis and migration which phenocopy the effects induced by septin depletion using siRNA.1 A useful tool for exploring the physiological role of septin and its complexes.3,4
Chemical PropertiesWhite Solid
Chemical PropertiesWhite to faint yellow crystalline powder.
UsesForchlorfenuronis is a diphenylurea-derivative cytokinin. Forchlorfenuronis is used as a plant growth regulator (PGR). Forchlorfenuronis is commonly used in horticulture to stimulate the growth of kiw i fruit and grapes.
Agricultural UsesPlant growth regulator: Forchlorfenuron is as a plant growth regulator to promote cell division, and to improve the quality and the yield of fruits, especially table grapes, grape raisins, and kiwi fruit. In some parts of California, forchlorfenuron is said to double the size of Thompson seedless grapes and delay crop maturity up to several weeks. widely used in agriculture on fruits to increase their size,
Trade nameCN-11-3183; KT-30®; SKW 20010
Potential ExposurePhenylurea/substituted urea plant growth regulator widely used in agriculture on fruits to increase their size, to promote cell division, and to improve the quality and the yield of fruits, especially table grapes, grape raisins, and kiwi fruit. In some parts of California, forchlorfenuron is reputed to double the size of Thompson seedless grapes and delay crop maturity up to several weeks.
ShippingUN2767 Phenyl urea pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
IncompatibilitiesMay react with strong oxidizers such as chlorates, peroxides, nitrates, etc. Dust may form explosive mixture with air.
Waste DisposalContainers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. If this material cannot be disposed of according to label instruc tions, it may be dissolved or mixed with a combustible sol vent and burned in a chemical incinerator equipped with an afterburner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers.
References1) Hu et al. (2008), Forchlorfenuron alters mammalian septin assembly, organization, and dynamics; J. Biol. Chem., 283 29563 2) DeMay et al. (2010), Cellular requirements for the small molecule forchlorfenuron to stabilize the septin cytoskeleton; Cytoskeleton, 67 383 3) Wasik et al. (2012), Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking; Mol. Biol. Cell, 23 3370 4) Vardi-Oknin et al. (2013), Forchlorfenuron disrupts SEPT9_i1 filaments and inhibits HIF-1; PLoS One, 8(8) e73179

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