Other grades of this product :
| Product Name: | X-PHOS | | Synonyms: | X-PHOS;5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE;2-(DICYCLOHEXYLPHOSPHINO)-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL;2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL;2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISOPROPYLBIPHENYL;2-Dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl, X-PHOS;2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl,min.98%X-Phos;-biphenyl]-2-yl]phosphane | | CAS: | 564483-18-7 | | MF: | C33H49P | | MW: | 476.72 | | EINECS: | 611-387-6 | | Product Categories: | Achiral Phosphine;Aryl Phosphine;Buchwald Ligands Series;Buchwald Ligands&Precatalysts | | Mol File: | 564483-18-7.mol |
| X-PHOS Chemical Properties |
| Melting point | 187-190 °C(lit.) | | Boiling point | 569.8±50.0 °C(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Benzene (Slightly) | | form | Powder | | color | white | | Sensitive | Air Sensitive | | Stability: | Air Sensitive | | InChIKey | UGOMMVLRQDMAQQ-UHFFFAOYSA-N | | CAS DataBase Reference | 564483-18-7(CAS DataBase Reference) |
| X-PHOS Usage And Synthesis |
| Reaction |
- Exceptional ligands for Pd-catalyzed amination and amidation of aryl sulfonates.
- Ligand used for the Pd-catalyzed Suzuki-Miyaura coupling reaction and carbonyl enolate coupling.
- Ligand used for the chemoselective amination of aryl chlorides.
- Ligand used for the Pd-catalyzed borylation of aryl chlorides, for the formation of trifluoroborates.
- Ligand used for the Pd-catalyzed amination of vinyl halides and triflates.
- Ligand used for the Pd-catalyzed three-component synthesis of indoles.
- Ligand used for the Pt-catalyzed regioselective hydrosilylation of functionalized terminal arylalkynes.
- Ligand used for the Pd-catalyzed synthesis of carbazoles.
- Ligand used for the Pd-catalyzed Suzuki-Miyaura coupling of aryl chloride and NHC-boranes.
- Ligand used for the direct arylation of picoline N-oxide.
- Ligand used for the Negishi coupling of 2-heterocyclic organozinc reagents.
- Catalyst for a phosphine-catalyzed Heine reaction.
- Ligand used for the palladium-catalyzed oxidative coupling of indoles and heteroarenes.
- Ligand used for the silver-catalyzed hydrogenation of aldehydes.
- Ligand used for the palladium-catalyzed cyanation of heterycyclic halides.
| | Chemical Properties | White crystalline powder | | Uses | suzuki reaction | | Uses | Exceptional ligands for Pd-catalyzed amination and amidation of aryl sulfonates. XPHOS is used as a regent in the synthesis of novel [1,2,4]triazolo[4,3-a]pyrazine derivatives as potential selective c-met inhibitors with improved pharmacokinetic properties. | | Uses | XPHOS is used as a regent in the synthesis of novel [1,2,4]triazolo[4,3-a]pyrazine derivatives as potential selective c-met inhibitors with improved pharmacokinetic properties. | | General Description | This product has been enhanced for catalytic efficiency. |
| X-PHOS Preparation Products And Raw materials |
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