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| 2'-Fluoro-2'-deoxyuridine Basic information |
| 2'-Fluoro-2'-deoxyuridine Chemical Properties |
| Melting point | 147.0 to 153.0 °C | | density | 1.63±0.1 g/cm3(Predicted) | | refractive index | 53 ° (C=0.3, H2O) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Soluble in methanol. | | pka | 9.39±0.10(Predicted) | | form | Powder | | color | White to Off-white | | InChIKey | UIYWFOZZIZEEKJ-XVFCMESISA-N | | CAS DataBase Reference | 784-71-4(CAS DataBase Reference) |
| 2'-Fluoro-2'-deoxyuridine Usage And Synthesis |
| Description | 2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. 2'-Deoxy-2'-fluorouridine has been shown to inhibit the replication of resistant mutants in vitro, and this inhibition can be reversed by increasing the concentration of 2'-deoxy-2'-fluorouridine. 2'-Deoxy-2'-fluorouridine also binds to duplexes of dsDNA with high affinity and specificity. | | Chemical Properties | White to almost white crystalline powder | | Uses | 2'-Fluoro-2'-deoxyuridine is used as a component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer. | | Uses | A component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer. |
| 2'-Fluoro-2'-deoxyuridine Preparation Products And Raw materials |
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