2,4-Dimethoxyaniline

2,4-Dimethoxyaniline
  • CAS No.:2735-04-8

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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2,4-Dimethoxyaniline Basic information
Product Name:2,4-Dimethoxyaniline
Synonyms:2,4-DIMETHOXYANILINE;2,4-DIMETHOXY BENZAMINE;4-AMINORESORCINOL;AKOS BBS-00003627;4-Aminoresorcinol dimethyl ether;Aniline, 2,4-dimethoxy-;aniline,2,4-dimethoxy-[qr];2,4-dimethoxybenzenamine
CAS:2735-04-8
MF:C8H11NO2
MW:153.18
EINECS:220-355-7
Product Categories:Amines;C8;Anilines, Aromatic Amines and Nitro Compounds;Nitrogen Compounds
Mol File:2735-04-8.mol
2,4-Dimethoxyaniline Chemical Properties
Melting point 33-36 °C (lit.)
Boiling point 75-80 C
density 1.075 g/mL at 25 °C (lit.)
refractive index 1.4640 (estimate)
Fp >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka5.14±0.10(Predicted)
form Crystalline Solid
color Dark brown
Water Solubility 7 g/L (20 ºC)
BRN 638704
Stability:Stability Stable, but sensitive to prolonged exposure to light. Incompatible with acids.
CAS DataBase Reference2735-04-8(CAS DataBase Reference)
NIST Chemistry ReferenceBenzenamine, 2,4-dimethoxy-(2735-04-8)
EPA Substance Registry System2,4-Dimethoxyaniline (2735-04-8)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38-20/21/22
Safety Statements 26-36-36/37/39-22
RIDADR 2811
WGK Germany 3
RTECS BX4200000
F 8-10-23
TSCA Yes
HazardClass 6.1(b)
PackingGroup III
HS Code 29214200
Hazardous Substances Data2735-04-8(Hazardous Substances Data)
MSDS Information
ProviderLanguage
2,4-Dimethoxyaniline English
ACROS English
SigmaAldrich English
ALFA English
2,4-Dimethoxyaniline Usage And Synthesis
Chemical Propertiesblack crystals
UsesVarious 2,4-dimethoxyphenylsemicarbazones were synthesized starting from 2,4-dimethoxyaniline via a phenylcarbamate intermediate. The hydrochloride of 2,4-dimethoxyaniline was prepared by intro- ducing hydrogen chloride gas into an etheral solution and washing the precipitate with absolute diethyl ether.
Synthesis Reference(s)Tetrahedron Letters, 34, p. 2441, 1993 DOI: 10.1016/S0040-4039(00)60436-7
General DescriptionBlack crystalline solid.
Air & Water ReactionsInsoluble in water.
Reactivity Profile2,4-Dimethoxyaniline neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health HazardACUTE/CHRONIC HAZARDS: 2,4-Dimethoxyaniline is a local irritant.
2,4-Dimethoxyaniline Preparation Products And Raw materials
Preparation ProductsBASIC YELLOW 11

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