Other grades of this product :
| 3-Chloropropiononitrile Basic information |
| 3-Chloropropiononitrile Chemical Properties |
| Melting point | -52--50 °C (lit.) | | Boiling point | 174-176 °C (lit.) | | density | 1.144 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.438(lit.) | | Fp | 168 °F | | storage temp. | Store below +30°C. | | solubility | 45g/l | | form | clear liquid | | color | Colorless to Almost colorless | | Water Solubility | 4.50 g/100 mL | | Merck | 14,2160 | | BRN | 1098454 | | CAS DataBase Reference | 542-76-7(CAS DataBase Reference) | | NIST Chemistry Reference | Cl(CH2)2CN(542-76-7) | | EPA Substance Registry System | 3-Chloropropionitrile (542-76-7) |
| Hazard Codes | T+ | | Risk Statements | 23-28 | | Safety Statements | 36/37/39-45 | | RIDADR | UN 3276 6.1/PG 2 | | WGK Germany | 3 | | RTECS | UG1400000 | | TSCA | Yes | | HazardClass | 6.1 | | PackingGroup | II | | HS Code | 29269095 | | Hazardous Substances Data | 542-76-7(Hazardous Substances Data) | | Toxicity | LD50 orally in mice, rats: 9, 100 mg/kg, Fassett in Industrial Hygiene and Toxicology vol. 2, F. A. Patty, Ed. (Interscience, New York, 2nd ed., 1962) pp 2025-2026 |
| 3-Chloropropiononitrile Usage And Synthesis |
| Chemical Properties | 3-Chloropropionitrile is a combustible, colorless liquid with an acrid odor | | Uses | In pharmaceutical and polymer synthesis. Combines the reactivity of a nitrile and an alkyl halide. Because of the cyano group the chlorine atom is more reactive than in ordinary alkyl halides. | | Uses | 3-Chloropropionitrile is used in pharmaceutical and polymer synthesis. | | General Description | Colorless liquid with a characteristic acrid odor. Used in pharmaceutical and polymer synthesis. | | Reactivity Profile | Toxic gas (hydrogen chloride) is released when the compound is heated above 266 F. When heated to decomposition, 3-Chloropropiononitrile emits very toxic fumes of chlorine- containing compounds and nitrogen oxides. Avoid heat. [EPA, 1998]. | | Hazard | Toxic by ingestion, inhalation, and skin
contact. Combustible. | | Health Hazard | Toxic effects are a result of systemic cyanide poisoning. (Non-Specific -- Cyanide) Few poisons are more rapidly lethal. Average oral lethal dose for hydrogen cyanide is approximately 60-90 mg (corresponds to 200 mg of potassium cyanide). Cause of death is lack of oxygen to the body's cells (especially the brain and heart) as a result of the chemical inhibiting cell enzymes. | | Fire Hazard | Toxic gas (hydrogen chloride) is released when the compound is heated above 266F. When heated to decomposition, 3-Chloropropiononitrile emits very toxic fumes of chlorine- containing compounds and nitrogen oxides. Avoid heat. | | Potential Exposure | This material is used in pharmaceutical manufacture and in polymer synthesis. | | Shipping | UN3276 Nitriles, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required, Potential Inhalation Hazard (Special Provision 5). | | Incompatibilities | Contact with strong oxidizers may cause a fire and explosion hazard |
| 3-Chloropropiononitrile Preparation Products And Raw materials |
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