GLYCOPROTEIN, ALPHA1-ACID HUMAN

GLYCOPROTEIN, ALPHA1-ACID HUMAN
  • CAS No.:66455-27-4
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GLYCOPROTEIN, ALPHA1-ACID HUMAN Basic information
Product Name:GLYCOPROTEIN, ALPHA1-ACID HUMAN
Synonyms:AGP;ALPHA1-ACID GLYCOPROTEIN;ALPHA1-ACID GLYCOPROTEIN, HUMAN;ALPHA1-ACID GLYCOPROTEIN, HUMAN SERUM;ALPHA1-ACID GLYCOPROTEIN (OROSOMUCOID);ALPHA-1 ACID GLYCOPROTEIN PLASMA;ALPHA1-AG, HUMAN;ALPHA-1-SEROMUCOID, HUMAN
CAS:66455-27-4
MF:NULL
MW:0
EINECS:
Product Categories:
Mol File:Mol File
GLYCOPROTEIN, ALPHA1-ACID HUMAN Chemical Properties
storage temp. 2-8°C
solubility H2O: 10 mg/mL, clear, colorless
form Lyophilized
Merck 13,8018
Safety Information
Hazard Codes B
Safety Statements 22-24/25
WGK Germany 3
10-21
MSDS Information
ProviderLanguage
SigmaAldrich English
GLYCOPROTEIN, ALPHA1-ACID HUMAN Usage And Synthesis
UsesGLYCOPROTEIN, ALPHA1-ACID HUMAN was used to study nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimine.
Usesα1-Acid glycoprotein from human plasma has been used:
  • as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayers
  • to incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISA
  • to study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors
General Descriptionα-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family.
Biochem/physiol Actionsα1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital.
Purification MethodsPurify the glycoprotein 1 acid by passage through a carboxymethyl cellulose column, then through a Sephadex G-25 column. [Aronson et al. J Biol Chem 243 4564 1968.]
GLYCOPROTEIN, ALPHA1-ACID HUMAN Preparation Products And Raw materials

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