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| BIOTINAMIDOCAPROYL HYDRAZIDE Basic information |
| BIOTINAMIDOCAPROYL HYDRAZIDE Chemical Properties |
| Melting point | 195-196°C | | Boiling point | 777.0±55.0 °C(Predicted) | | density | 1.188±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: 25 mg/mL | | form | powder | | pka | 13.26±0.35(Predicted) | | color | White to Almost white | | InChIKey | IJJWOSAXNHWBPR-HUBLWGQQSA-N | | CAS DataBase Reference | 109276-34-8(CAS DataBase Reference) |
| BIOTINAMIDOCAPROYL HYDRAZIDE Usage And Synthesis |
| Description | This is a hydrazide-activated biotinylation reagent used to label glycoproteins, carbohydrate-containing compounds that have oxidizable sugars or aldehydes. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds. The extended spacer arm helps to minimize steric hindrance. | | Chemical Properties | mp 195°C | | Uses | Biotinylation reagent with aminocaproic spacer for aldehyde groups (e.g., periodate-oxidized sugars) and carboxylic acids. Typically used for coupling to glycoproteins through the carbohydrate by hydrazone bond formation. | | Purification Methods | Suspend the hydrazide in ice-water (100mg/mL), stand overnight at 4o, filter and dry the solid in a vacuum. Recrystallise it from isoPrOH. RF is 0.26 on SiO2 plate using CHCl3/MeOH (7:3) as eluent. [O'Shannessy et al. Anal Biochem 163 204 1987.] |
| BIOTINAMIDOCAPROYL HYDRAZIDE Preparation Products And Raw materials |
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