![4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE](/img/109806-71-5.jpg "4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE")
| 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Basic information |
| Product Name: | 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE |
| Synonyms: | 2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZIN-1-YL}-ETHANOL;2-[4-{Chlorophenyl}Phenylmethyl]-1-;2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol;Levocetirizine Impurity G;4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone;1-Piperazineethanol, 4-[(4- chlorophenyl)phenylMethyl]-;(R)-2-(4-((4-chlorophenyl);Levocetirizine Impurity 6 |
| CAS: | 109806-71-5 |
| MF: | C19H23ClN2O |
| MW: | 330.85 |
| EINECS: | |
| Product Categories: | (intermediate of cetirizine dihydrochloride) |
| Mol File: | 109806-71-5.mol |
| 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Chemical Properties |
| Boiling point | 205-208 °C(Press: 0.1 Torr) |
| density | 1.191±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 14.96±0.10(Predicted) |
| color | White to Off-White Sticky to Low-Melting |
| Stability: | Very Hygroscopic |
| CAS DataBase Reference | 109806-71-5(CAS DataBase Reference) |
| Safety Information |
| MSDS Information |
| 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Usage And Synthesis |
| Chemical Properties | Off-White Solid |
| Uses | 2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethanol is an impurity of (R)-Cetirizine (C281106). |
| Uses | 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine. |
| 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Preparation Products And Raw materials |
| Raw materials | Tetrahydrofuran-->Dichloromethane-->Thionyl chloride-->Toluene-->Triethylamine-->Benzene-->1,4-Dioxane-->Sodium borohydride-->Isopropyl alcohol-->Piperazine-->Calcium chloride-->2-Bromoethanol-->4-Chlorobenzophenone-->1-(4-Chlorobenzhydryl)piperazine |
| Preparation Products | 1-Piperazineacetaldehyde-->Cetirizine |
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