Trifluoro-p-tolunitrile

CAS No.：455-18-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

Trifluoro-p-tolunitrile Basic information

Product Name:	Trifluoro-p-tolunitrile
Synonyms:	PTF-CN;P-TRIFLUOROMETHYLBENZONITRILE;PARA-TRIFLUOROMETHYL-BENZONITRILE;trifluoro-p-tolunitrile;4-CYANOBENZOTRIFLUORIDE;4-(TRIFLUOROMETHYL)BENZONITRILE;ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLUNITRILE;alpha,alpha,alpha-Trifluoro-p-toluonitrile
CAS:	455-18-5
MF:	C8H4F3N
MW:	171.12
EINECS:	207-239-1
Product Categories:	cyanide;Aromatic Nitriles;Drug Intermediates;Fluorine Compounds;Nitriles;Benzotrifluoride Series;Nitrile;bc0001;455-18-5
Mol File:	455-18-5.mol

Trifluoro-p-tolunitrile Chemical Properties

Melting point	39-41 °C(lit.)
Boiling point	80-81 °C20 mm Hg(lit.)
density	1.278 g/mL at 25 °C(lit.)
refractive index	n20/D 1.4583(lit.)
Fp	161 °F
storage temp.	Sealed in dry,Room Temperature
Water Solubility	Insoluble in water
form	powder to lump to clear liquid
color	White or Colorless to Light yellow
Specific Gravity	1.278
Sensitive	Lachrymatory
BRN	2046478
InChIKey	DRNJIKRLQJRKMM-UHFFFAOYSA-N
CAS DataBase Reference	455-18-5(CAS DataBase Reference)
NIST Chemistry Reference	4-Trifluoromethylbenzoic acid nitrile(455-18-5)
EPA Substance Registry System	Benzonitrile, 4-(trifluoromethyl)- (455-18-5)

Safety Information

Hazard Codes	Xn,F
Risk Statements	20/21/22-11
Safety Statements	36/37-45-36
RIDADR	UN 1325 4.1/PG 2
WGK Germany	3
Hazard Note	Lachrymatory
TSCA	T
HazardClass	6.1
PackingGroup	III
HS Code	29269095

MSDS Information

Provider	Language
4-(Trifluoromethyl)benzonitrile	English
SigmaAldrich	English
ACROS	English
ALFA	English

Trifluoro-p-tolunitrile Usage And Synthesis

Chemical Properties	white to light yellow crystal powder
General Description	4-(Trifluoromethyl)benzonitrile is a key intermediate in the synthesis of fluvoxamine. It participates in nickel-catalyzed arylcyanation reaction of 4-octyne.

Trifluoro-p-tolunitrile Preparation Products And Raw materials

Preparation Products

4-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE-->5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-->4-(Difluoromethyl)benzonitrile

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873