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| N-succinimidyl-4-((iodoacetyl)amino)benzoate Basic information |
| N-succinimidyl-4-((iodoacetyl)amino)benzoate Chemical Properties |
| Melting point | 19-7-200°C (dec.) | | density | 1.87±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 12.16±0.70(Predicted) |
| N-succinimidyl-4-((iodoacetyl)amino)benzoate Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Uses | A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 10.6 Angstroms | | Uses | A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent.
Spacer Arm: 10.6 Angstroms | | General Description | SIAB is an amine- and sulfhydryl-reactive heterobifunctional crosslinker and Sulfo-SIAB is its water-soluble analog. These crosslinkers contain an amine-reactive N-hydroxysuccimide (NHS) ester and a sulfhydryl-reactive iodoacetyl group, and are often used for preparing enzyme conjugates or immunotoxins. Water-soluble and water-insoluble forms of NHS esters have essentially identical reactivity. Sulfo-SIAB is supplied as a sodium salt and is water-soluble to ~10mM. SIAB must be first dissolved in an organic solvent, such as DMSO or DMF, and then added to the aqueous reaction mixture. SIAB is lipophilic, membrane-permeable and does not possess a charged group. |
| N-succinimidyl-4-((iodoacetyl)amino)benzoate Preparation Products And Raw materials |
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