Phthalylglycyl chloride

CAS No.：6780-38-7

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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Phthalylglycyl chloride Basic information

Product Name:	Phthalylglycyl chloride
Synonyms:	Phthalyl-glycyl chloride ,98%;(1,3-Dioxo-2H-isoindole-2-yl)acetyl chloride;1,3-Dihydro-1,3-dioxo-2H-isoindole-2-acetic acid chloride;2-(Phthalimidyl)acetyl chloride;2-Phthalimidylacetic acid chloride;N-(2-Chloro-2-oxoethyl)phthalimide;N,N-Phthaloylglycine chloride;2-(1,3-dioxoisoindolin-2-yl) acetyl chloride
CAS:	6780-38-7
MF:	C10H6ClNO3
MW:	223.61
EINECS:	229-840-8
Product Categories:	Acid Halides;Carbonyl Compounds;pharmacetical;Organic Building Blocks;Acid Halides;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Heterocycle-other series
Mol File:	6780-38-7.mol

Phthalylglycyl chloride Chemical Properties

Melting point	84-85 °C
Boiling point	190-192 °C(Press: 15 Torr)
density	1.504±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Chloroform, Dichloromethane
form	Solid
pka	-2.56±0.20(Predicted)
color	White

Safety Information

Hazard Codes	T
Risk Statements	25-34
Safety Statements	26-36/37/39-45
RIDADR	UN 2923 8/PG 3
WGK Germany	3
HazardClass	IRRITANT

MSDS Information

Provider	Language
SigmaAldrich	English

Phthalylglycyl chloride Usage And Synthesis

Chemical Properties	slight yellow to white crystalline powder
Uses	Reactant involved in:• ;Synthesis of selenium-containing amino acid analogs with bactericidal and antifungal activity1• ;Photoinduced single electron transfer cyclization for preparation of cyclic peptides2• ;Arndt-Eistert synthesis3• ;Mitsunobu and arbuzov-type multicomponent pathway4• ;Remote C-H bond functionalization5• ;Amido-alkylation for synthesis of benzofuran derivatives6
Uses	Phthalylglycyl chloride can be used in the synthesis of N-Phthalimidoacetyl-β-phenylethylamnine.
General Description	Phthalylglycyl chloride can be synthesized via reaction of phthalyl-glycine with thionyl chloride.

Phthalylglycyl chloride Preparation Products And Raw materials

Preparation Products

H-GLY-CYS-OH-->6-(Phthalimidomethyl)morphanthridine

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