Phenyl vinyl sulfone

Phenyl vinyl sulfone
  • CAS No.:5535-48-8
Other grades of this product :
Phenyl vinyl sulfone Basic information
Product Name:Phenyl vinyl sulfone
Synonyms:VINYL PHENYL SULFONE;Eletriptan intermediate 1;Phenylvinylsulfone,99+%;Benzene, (ethenylsulfonyl)-;1,1'-Sulfonylbis(ethene-1,1-diyl)dibenzene;Phenyl vinyl sulphone, 99+%;1-(Phenylsulfonyl)ethene;(ethenesulfonyl)benzene
CAS:5535-48-8
MF:C8H8O2S
MW:168.21
EINECS:226-890-2
Product Categories:Bioactive Small Molecules;Building Blocks;Cell Biology;Chemical Synthesis;Organic Building Blocks;P;Pharmaceutical material and intermeidates;Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;Naphthyridine,Quinoline;Organic Building Blocks;Sulfones;Sulfur Compounds;Sulfur Compounds
Mol File:5535-48-8.mol
Phenyl vinyl sulfone Chemical Properties
Melting point 67-69 °C (lit.)
Boiling point 267.16°C (rough estimate)
density 1.2660 (rough estimate)
refractive index 1.5090 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility It is soluble in most common organic solvents.
form Solid
color White
BRN 1906894
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyUJTPZISIAWDGFF-UHFFFAOYSA-N
CAS DataBase Reference5535-48-8(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, (ethenylsulfonyl)-(5535-48-8)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-43-41-37/38-22
Safety Statements 26-36/37/39-37/39
WGK Germany 3
HS Code 29309090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
Phenyl vinyl sulfone Usage And Synthesis
Chemical Propertiesoff-white or tan powder
UsesAs common reagent, Phenyl vinyl sulfone is used in a variety of cycloaddition reactions to form cyclopropanes,1 cyclohexenes,2,3 and cyclooctadienes.
UsesPhenyl Vinyl Sulfone is a synthetic inhibitor of cysteine protease and has antihelminthic and antiprotozoal properties. Phenyl Vinyl Sulfone is also an inhibitor of transpeptidase SrtA required for cell wall protein anchoring and virulence in Staphylococcus aureus.
Synthesis Reference(s)The Journal of Organic Chemistry, 48, p. 4976, 1983 DOI: 10.1021/jo00173a039
General DescriptionPhenyl vinyl sulfone, a synthetic inhibitor of cysteine protease, exhibits antihelminthic and antiprotozoal properties.

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