| 4-Chloro-3-fluoroaniline Basic information |
| Uses |
| Product Name: | 4-Chloro-3-fluoroaniline |
| Synonyms: | 4-CHLORO-3-FLUORO-PHENYLAMINE;4-CHLORO-3-FLUOROANILINE;3-FLUORO-4-CHLOROANILINE;BUTTPARK 44\01-97;4-chloro-3-fluorobenzenaMine;4-Chloro-3-fluoroanline;4-Chloro-3-fluoroaniline 98%;4-Chloro-3-fluoroaniline98% |
| CAS: | 367-22-6 |
| MF: | C6H5ClFN |
| MW: | 145.56 |
| EINECS: | 206-683-3 |
| Product Categories: | Aryl Fluorinated Building Blocks;Building Blocks;C6;Chemical Synthesis;Fluorinated Building Blocks;Organic Fluorinated Building Blocks;Anilines, Aromatic Amines and Nitro Compounds;Aniline;Other Fluorinated Organic Building Blocks |
| Mol File: | 367-22-6.mol |
| 4-Chloro-3-fluoroaniline Chemical Properties |
| Melting point | 61 |
| Boiling point | 226°C(lit.) |
| density | 1.349±0.06 g/cm3(Predicted) |
| Fp | 60 - 62°C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | soluble in Methanol |
| pka | 2.94±0.10(Predicted) |
| form | powder to crystal |
| color | White to Gray to Red |
| BRN | 2716278 |
| CAS DataBase Reference | 367-22-6(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | T,Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36/37/39-63-45-38 |
| RIDADR | UN2811 |
| WGK Germany | 3 |
| Hazard Note | Toxic |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29214200 |
| MSDS Information |
| 4-Chloro-3-fluoroaniline Usage And Synthesis |
| Uses | 4-Chloro-3-fluoroaniline is used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate; a key intermediate towards phosphoindole inhibitors of HIV non-nucleoside reverse transcriptase. 4-Chloro-3-fluoroaniline is also used in the synthesis of 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib (D289540) which is an impurity of the tyrosine kinase inhibitor Gefitinib. |
| Chemical Properties | White to light yellow solid |
| 4-Chloro-3-fluoroaniline Preparation Products And Raw materials |
| Preparation Products | 4-Chloro-2-fluoroaniline |
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.
日本语
한국어
Français
Deutsch
España
Türkiye