| 3-(Trifluoromethyl)pyridine-2-carboxylic acid Basic information |
| Product Name: | 3-(Trifluoromethyl)pyridine-2-carboxylic acid |
| Synonyms: | 3-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXYLIC ACID;3-(TRIFLUOROMETHYL)PICOLINIC ACID;3-(TRIFLUOROMETHYL)-2-PICOLINIC ACID;3-(trifluoromethyl)-2-pyridinecarboxylic acid;3-(Trifluoromethy)pyridine-2-carboxylic acid;3-(Trifluoromethyl)-2-pyridinecarboxylicacid(en);3-(Trifluoromethyl)picolinic acid, 2-Carboxy-3-(trifluoromethyl)pyridine;2-Pyridinecarboxylic acid, 3-(trifluoromethyl)- |
| CAS: | 87407-12-3 |
| MF: | C7H4F3NO2 |
| MW: | 191.11 |
| EINECS: | |
| Product Categories: | Carboxylic Acids;Pyridines;Acids and Derivatives;Heterocycles;Carboxylic Acids;Fluorine series;Aromatics;Intermediates |
| Mol File: | 87407-12-3.mol |
| 3-(Trifluoromethyl)pyridine-2-carboxylic acid Chemical Properties |
| Melting point | 125-130°C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Off-White |
| Safety Information |
| Hazard Codes | Xi,T |
| Risk Statements | 25-36/37/38 |
| Safety Statements | 26-45 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| PackingGroup | Ⅲ |
| HS Code | 2933399990 |
| MSDS Information |
| 3-(Trifluoromethyl)pyridine-2-carboxylic acid Usage And Synthesis |
| Uses | As Picolinic acid (P437220) derivative, 3-(Trifluoromethyl)pyridine-2-carboxylic acid can be used in the synthesis of oxazine derivatives that act as BACE inhibitors for treatment of diabetes and neurological disorders. |
| Uses | Picolinic acid (P437220) derivative used in the synthesis of oxazine derivatives that act as BACE inhibitors for treatment of diabetes and neurological disorders. |
| Synthesis Reference(s) | Tetrahedron, 50, p. 12259, 1994 DOI: 10.1016/S0040-4020(01)89575-2 |
| 3-(Trifluoromethyl)pyridine-2-carboxylic acid Preparation Products And Raw materials |
| Raw materials | 2-Bromo-3-trifluoromethylpyridine-->2-Chloro-3-(trifluoromethyl)pyridine-->3-Trifluoromethylpyridine-->CARBON DIOXIDE |
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