Tebufenpyrad

Tebufenpyrad
  • CAS No.:119168-77-3
Other grades of this product :
Tebufenpyrad Basic information
Product Name:Tebufenpyrad
Synonyms:TEBUFENPYRAD;PYRANICA;OSCAR;1h-pyrazole-5-carboxamide,4-chloro-n-((4-(1,1-dimethylethyl)phenyl)methyl)-3-e;4-chloro-n-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1h-pyrazol;4-chloro-n-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1h-pyrazole-5-carboxamid;ac801757;comanché
CAS:119168-77-3
MF:C18H24ClN3O
MW:333.86
EINECS:242-070-7
Product Categories:Agro-Products;Aromatics;Herbicide;INSECTICIDE;Heterocycles
Mol File:119168-77-3.mol
Tebufenpyrad Chemical Properties
Melting point 61-62°
Boiling point 468.4±45.0 °C(Predicted)
density 1.1639 (rough estimate)
refractive index 1.5790 (estimate)
storage temp. 0-6°C
pka13.19±0.46(Predicted)
form neat
BRN 8636471
CAS DataBase Reference119168-77-3(CAS DataBase Reference)
EPA Substance Registry SystemTebufenpyrad (119168-77-3)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 36
RIDADR 2588
WGK Germany 3
RTECS UQ6276400
HazardClass 6.1(b)
PackingGroup III
HS Code 29331990
Hazardous Substances Data119168-77-3(Hazardous Substances Data)
ToxicityLD50 in male, female rats (mg/kg): 595, 997 orally; >2000, >2000 dermally; LC50 in male rats (mg/m3): 2660 by inhalation (Inoue, Fukuchi)
MSDS Information
Tebufenpyrad Usage And Synthesis
Chemical PropertiesTan Solid
UsesTebufenpyrad is a pyrazole acaricide and insecticide commonly used in commercial greenhouses.
UsesAcaricide.
Metabolic pathwayBy incubation of tebufenpyrad with rat liver homogenate, tebufenpyrad undergoes biotransformation to yield the major metabolites N-(4- tert-butylbenzyl)-4-chloro-3-(1-hydroxyethyl)-1- methylpyrazole-5-carboxamide via hydroxylation of the w-1-carbon of the ethyl group and N-[4-(1-carboxy-1- methylethyl)benzyl]-4-chloro-3-ethyl-1-methylpyrazole- 5-carboxamide via oxidation of the methyl group in the tert-butyl moiety to the carboxylic acid derivatives.When the rat is orally dosed tebufenpyrad, the major metabolism pathway is via both hydroxylation and oxidation reactions to yield N-[4-(1-carboxy-1- methylethyl)benzyl]-4-chloro-3-(1-hydroxyethyl)-1- methylpyrazole-5-carboxamide which is mainly excreted in the urine.
Tebufenpyrad Preparation Products And Raw materials
Raw materialsDiethyl oxalate-->Sulfuryl chloride-->ethyl 3-ethylpyrazolyl-5-carboxylate-->N-(tert-Butyl)benzylamine

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