1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC)

CAS No.：851477-20-8

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1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC) Basic information

Reaction

Product Name:	1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC)
Synonyms:	1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC);1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea (S,S-TUC);1-[3,5-Bis(trifluoroMethyl)phenyl]-3-[(1S,2S) -2-(diMethylaMino)cyclohexyl]thiourea;Thiourea, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(diMethylaMino)cyclohexyl]-;1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-2- (dimethylamino)cyclohexyl]thiourea,99%e.e.;1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-2-(dimethylamino)cyclohexyl]thiourea, 98%, (99% ee);851477-20-8
CAS:	851477-20-8
MF:	C17H21F6N3S
MW:	413.42
EINECS:
Product Categories:	organic amine
Mol File:	851477-20-8.mol

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC) Chemical Properties

Melting point	87-88°C
alpha	+42° (c 1.16, CHCl3)
Boiling point	380.8±52.0 °C(Predicted)
density	1.33±0.1 g/cm3(Predicted)
storage temp.	2-8°C
form	Powder
pka	11.76±0.70(Predicted)
color	white

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MSDS Information

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC) Usage And Synthesis

Reaction

Thiourea catalyst used in the enantio and diastereoselective Michael addition of malonates and ketoesters to nitroolefins.
Catalyst used in the enantioselective hydrazination of 1,3-dicarbonyl compounds.
Catalyst used for the dynamic resolution of azalactones.
Catalyst used in Michael-Aldol reaction of 2-mercaptobenzaldehyde with α,β-unsaturated oxazolidinone.
Catalyst for enantioselective synthesis of flavanones and chromanones.
Catalyst for the asymmetric Neber Reaction.
Catalyst for the three component synthesis of 2,6-diazabicyclo[2.2.2]octanones.

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC) Preparation Products And Raw materials

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