METHYL ACETIMIDATE HYDROCHLORIDE

METHYL ACETIMIDATE HYDROCHLORIDE
  • CAS No.:14777-27-6
Other grades of this product :
METHYL ACETIMIDATE HYDROCHLORIDE Basic information
Product Name:METHYL ACETIMIDATE HYDROCHLORIDE
Synonyms:acetimidicacid,methylester,hydrochloride;ethanimidicacid,methylester,hydrochloride;METHYL ACETIMIDATE HCL;METHYL ACETIMIDATE HYDROCHLORIDE;METHYL ACETIMIDATE HYDROCHLORIDE, TECH.;AcetimidicacidmethylesterHCl;Methyl acetiMidate hydrochloride , Technical;Methyl acetimidate hydrochloride technical grade
CAS:14777-27-6
MF:C3H8ClNO
MW:109.55
EINECS:238-843-3
Product Categories:Amidates/Imidates;Nitrogen Compounds;Organic Building Blocks
Mol File:14777-27-6.mol
METHYL ACETIMIDATE HYDROCHLORIDE Chemical Properties
Melting point 105 °C (dec.)(lit.)
storage temp. 2-8°C
BRN 3671581
EPA Substance Registry SystemEthanimidic acid, methyl ester, hydrochloride (14777-27-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS AK2950000
10-21
HS Code 2929900090
MSDS Information
ProviderLanguage
SigmaAldrich English
METHYL ACETIMIDATE HYDROCHLORIDE Usage And Synthesis
Chemical PropertiesWhite to yellow powder
UsesMethyl acetimidate hydrochloride has been used in pre-crystallization chemical modification of lysine residues.
General DescriptionMethyl acetimidate hydrochloride is an inhibitor of N-methylation of phosphatidylethanolamine. It also prevents the stimulation of purified cardiac sarcolemmal vesicles Ca2+-pump activities.
Purification MethodsCrystallise the imidate from methanol by adding dry ether to a ratio of 1:1 and cooling at 0o. Filter off the crystals in a cold room, wash them with methanol/ether (1:2), then dry in a vacuum. [Hunter & Ludwig J Am Chem Soc 84 3491 1962.] The free base has b 90-91o/765mm, d 0.867, n 1.403. [Hunter & Ludwig Methods Enzymol 25 585 1973, Beilstein 2 IV 181.]
METHYL ACETIMIDATE HYDROCHLORIDE Preparation Products And Raw materials
Preparation ProductsMethyl N-cyanoethanimideate-->4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE

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